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Page 8 of 23                                                                               George et al. Mini-invasive Surg 2024;8:4  https://dx.doi.org/10.20517/2574-1225.2023.102



                                                                                                                                         5,000 patients
                                       [33]
                              Majid et al.   Erosions and   2020        Retrospective         Pakistan   Using multi-type features       Training: 6,922 images of bleeding,   CNN     Sensitivity of 96.5%
                                             ulcers                                                      extraction, fusion, and features   oesophagitis, polyp, and ulcerative colitis
                                                                                                         selection to detect ulcer, polyp,   Testing: 2,967 images of bleeding,
                                                                                                         esophagitis, and bleeding       oesophagitis, polyp, and ulcerative colitis
                                        [29]
                              Kundu et al.   Erosions and   2020        Retrospective         Bangladesh Employing LDA for ROI separation  Training: 65 bleeding, 31 ulcers,   SVM     Sensitivity of 85.96%,
                                             ulcers                                                                                      and 30 tumour images                          specificity of 92.24%
                                                                                                                                         Testing: 15 continuous video clips
                                       [34]
                              Otani et al.   Erosions and   2020        Retrospective         Japan      Multiple lesion detection using   Database of 398 images of erosions and  Deep   No sensitivity and
                                             ulcers                                                      RetinaNet                       ulcers, 538 images of angiodysplasias,   neural   specificity reported
                                                                                                                                         4,590 images of tumours, and 34,437   network
                                                                                                                                         normal images for training and testing
                                     [35]
                              Xia et al.     Erosions and   2021        Retrospective         China      Novel CNN and RCNN system to    Training: 822,590 images            CNN,      Sensitivity of 96.2%, specificity
                                             ulcers                                                      detect 7 types of lesions in MCE   Testing: 201,365 images          RCNN      of 76.2%
                                                                                                         imaging
                                         [36]
                              Afonso et al.  Erosions and   2021        Retrospective         Portugal   Identify but also differentiate ulcers  Training: 18,976 images     CNN       Sensitivity of 86.6%, specificity
                                             ulcers                                                      and erosions based on           Testing: 4,744 images                         of 95.9%
                                                                                                         haemorrhagic potential
                              Mascarenhas    Erosions and   2021        Retrospective         Portugal   Identify various lesions on CE   Training: 42,844 images            CNN       Sensitivity of 88%, specificity
                                         [37]
                              Saraiva et al.  ulcers                                                     images and differentiate using   Testing: 10,711 images                       of 99%
                                                                                                         Saurin’s classification
                                         [38]
                              Afonso et al.  Erosions and   2022        Retrospective         Portugal   Identify but also differentiate ulcers  Training: 4,904 images      CNN       Sensitivity of 90.8%, specificity
                                             ulcers                                                      and erosions based on           Testing: 379 normal images, 266 erosion,      of 97.1%
                                                                                                         haemorrhagic potential          286 P1 Ulcer images, 295 P2 Ulcer
                                                                                                                                         images
                              Mascarenhas    Erosions and   2022        Retrospective         Portugal   Develop CNN-based method to     Training: 7,204 images              CNN       Sensitivity of 96.3%, specificity
                                  [39]
                              et al.         ulcers                                                      detect and distinguish colonic   Testing: 1,801                               of 98.2%
                                                                                                         mucosal lesions and luminal blood
                                                                                                         in CCE imaging
                                      [40]
                              Xiao et al.    Erosions and   2022        Retrospective         China      Classify capsule gastroscope    Training: 228 images                CNN       No sensitivity and specificity,
                                             ulcers                     sensitivity of 96.9%             images into normal, chronic erosive  Testing: 912 images                      accuracy of 94.81%
                                                                        and a specificity of             gastritis, and gastric ulcer
                                                                        99.9% specific                   categories
                                        [41]
                              Ribeiro et al.  Erosions and   2022       Retrospective         Portugal   Accurately detect ulcers and    Training: 26,869 images             CNN       Sensitivity of 96.9%, specificity
                                             ulcers                                                      erosions in CCE images          Testing: 3,375 normal images, 357             of 99.9%
                                                                                                                                         images with ulcers or colonic erosions
                                         [43]
                              Nakada et al.  Erosions and   2023        Retrospective         Japan      Utilise RetinaNet to diagnose   Training: 6,476 erosion and ulcer images,  Deep   Erosions and ulcers: sensitivity
                                             ulcers                                                      erosions and ulcers, vascular   1,916 angiodysplasias images, 7,127   neural   of 91.9%, specificity of 93.6%
                                                                                                         lesions, and tumours in WCE     tumour images, 14,014,149 normal    network   Vascular lesions:
                                                                                                         imaging                         images                                        sensitivity of 87.8%,
                                                                                                                                         Testing: images from 217 patients             specificity of 96.9%
                                                                                                                                                                                       Tumours: sensitivity of 87.6%,
                                                                                                                                                                                       specificity of 93.7%
                                      [42]                                                                                                                             [110]
                              Raut et al.    Erosions and   2023        Retrospective         India      Use various feature extraction   Training and testing on KID dataset  Deep    Sensitivity of 97.23%,
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