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Aminisani et al. J Cancer Metastasis Treat 2017;3:209-16 Journal of
DOI: 10.20517/2394-4722.2017.47
Cancer Metastasis and Treatment

www.jcmtjournal.com
Original Article Open Access

Health-related quality of life and its

correlates among rectal cancer survivors,

Northwest of Iran

Nayyereh Aminisani , Mehdi Fatemi , Parvin Sarbakhsh , Alireza Nikanfar , Amirtaher Eftekharsadat ,
2
3
1
1
1
Esmat Jafari 1
1 Epidemiology and Statistics Department, Faculty of Health Sciences, Tabriz University of Medical Sciences, Tabriz 5165665931, Iran.
2 Haematology and Oncology Research Center of Tabriz University of Medical Sciences, Tabriz 5165665123, Iran.
3 Pathology Department, Emam Reza Hospital, Tabriz 5165665123, Iran.
Correspondence to: Dr. Nayyereh Aminisani, Epidemiology and Statistics Department, Faculty of Health Sciences, Tabriz University of Medical
Sciences, Tabriz 5165665931, Iran. E-mail: aminisani_n@hotmail.com
How to cite this article: Aminisani N, Fatemi M, Sarbakhsh P, Nikanfar A, Eftekharsadat A, Jafari E. Health-related quality of life and its correlates
among rectal cancer survivors, Northwest of Iran. J Cancer Metastasis Treat 2017;3:209-16.
ABSTRACT
Article history: Aim: The objective of this study was to examine the health-related quality of life
Received: 14 Jul 2017 (HRQOL), and its correlates among rectal cancer survivors. Methods: This cross-sectional
Accepted: 21 Sep 2017 study was conducted in the northwest of Iran. Rectal cancer survivors were selected from
Published: 29 Sep 2017 teaching hospitals. HRQOL was estimated using the European Organization for Research
and Treatment of Cancer Quality-of-Life Questionnaire C30. Information about socio-
Key words: demographic, lifestyle and clinical features of disease was obtained by trained interviewers.
Health, Results: A total of 96 patients were included in this study with mean age of 57.31 ± 14.15
quality of life, years, 54% were male and 59% over 55 years of age. Women performed poorer than men
rectal cancer, in many dimensions of HRQOL (P < 0.05). Total score of symptoms was higher in those
treatment, who had a higher stage of the disease. Participants with insufficient physical activity had
socioeconomic status a lower score in physical and role dimensions and a higher score of pain and fatigue (P
< 0.05). In multiple regression models, treatment, stage of disease, and physical activity
were important predictive factors of HRQOL. Conclusion: Some clinico-epidemiological
factors were associated with a reduced score of HRQOL and its dimensions in this study.
Overall, better performance in the presence of a modifiable factor; physical activity, is an
opportunity for interventional strategies to improve the HRQOL.

INTRODUCTION deaths in 2012 . There is a geographical variation in
[1]
the incidence of CRC around the globe with over 10-fold
Colorectal cancer (CRC) is the second common cancer difference between the highest and lowest estimated
in female and the third in men, with an estimation of incidence in 2012. The highest incidence has been
about 1.5 million incident cases and almost 700,000 reported from Australia, New Zealand, Europe and

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