Page 83 - Read Online

Page 14 of 14 Maisel et al. J Cancer Metastasis Treat 2019;5:7 I http://dx.doi.org/10.20517/2394-4722.2018.82

like domains. J Cell Biol 1998;141:905-15.
126. Barton DP, Blanchard DK, Wells AF, Nicosia SV, Roberts WS, et al. Expression of interleukin-2 receptor alpha (IL-2R alpha) mRNA and
protein in advanced epithelial ovarian cancer. Anticancer Res 1994;14:761-72.
127. Tefferi A, Vaidya R, Caramazza D, Finke C, Lasho T, et al. Circulating interleukin (IL)-8, IL-2R, IL-12, and IL-15 levels are independently
prognostic in primary myelofibrosis: a comprehensive cytokine profiling study. J Clin Oncol 2011;29:1356-63.
128. Zwaagstra JC, Guimond A, O’Connor-McCourt MD. Predominant intracellular localization of the type I transforming growth factor-beta
receptor and increased nuclear accumulation after growth arrest. Exp Cell Res 2000;258:121-34.
129. Forrester E, Chytil A, Bierie B, Aakre M, Gorska AE, et al. Effect of conditional knockout of the type II TGF-beta receptor gene in
mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis. Cancer
Res 2005;65:2296-302.
130. Heldin CH, Landström M, Moustakas A. Mechanism of TGF-beta signaling to growth arrest, apoptosis, and epithelial-mesenchymal
transition. Curr Opin Cell Biol 2009;21:166-76.
131. Hayes S, Chawla A, Corvera S. TGF beta receptor internalization into EEA1-enriched early endosomes: role in signaling to Smad2. J Cell
Biol 2002;158:1239-49.
132. Di Guglielmo GM, Le Roy C, Goodfellow AF, Wrana JL. Distinct endocytic pathways regulate TGF-beta receptor signalling and turnover.
Nat Cell Biol 2003;5:410-21.
133. Stechmann B, Bai SK, Gobbo E, Lopez R, Merer G, et al. Inhibition of retrograde transport protects mice from lethal ricin challenge. Cell
2010;141:231-42.
134. Luginbuehl V, Meier N, Kovar K, Rohrer J. Intracellular drug delivery: potential usefulness of engineered Shiga toxin subunit B for targeted
cancer therapy. Biotechnol Adv 2018;36:613-23.
135. Lo HW, Hung MC. Nuclear EGFR signalling network in cancers: linking EGFR pathway to cell cycle progression, nitric oxide pathway and
patient survival. Br J Cancer 2006;94:184-8.
136. Giri DK, Ali-Seyed M, Li LY, Lee DF, Ling P, et al. Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface
receptor. Mol Cell Biol 2005;25:11005-18.
137. Dittmann K, Mayer C, Rodemann HP. Inhibition of radiation-induced EGFR nuclear import by C225 (Cetuximab) suppresses DNA-PK
activity. Radiother Oncol 2005;76:157-61.
138. Pilarczyk G, Nesnidal I, Gunkel M, Bach M, Bestvater F, et al. Localisation microscopy of breast epithelial ErbB-2 receptors and
gap junctions: trafficking after gamma-irradiation, neuregulin-1beta, and trastuzumab application. Int J Mol Sci 2017; doi: 10.3390/
ijms18020362.
139. Hintersteiner M, Ambrus G, Bednenko J, Schmied M, Knox AJ, et al. Identification of a small molecule inhibitor of importin beta mediated
nuclear import by confocal on-bead screening of tagged one-bead one-compound libraries. ACS Chem Biol 2010;5:967-79.
140. Cordero JB, Cozzolino M, Lu Y, Vidal M, Slatopolsky E, et al. 1,25-Dihydroxyvitamin D down-regulates cell membrane growth- and
nuclear growth-promoting signals by the epidermal growth factor receptor. J Biol Chem 2002;277:38965-71.