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Page 12 of 14                          Maisel et al. J Cancer Metastasis Treat 2019;5:7  I  http://dx.doi.org/10.20517/2394-4722.2018.82

                   metastasis. Breast Cancer Res Treat 2014;143:435-46.
               58.  Coleman SJ, Chioni AM, Ghallab M, Anderson RK, Lemoine NR, et al. Nuclear translocation of FGFR1 and FGF2 in pancreatic stellate
                   cells facilitates pancreatic cancer cell invasion. EMBO Mol Med 2014;6:467-81.
               59.  Yarden Y, Sliwkowski MX. Untangling the ErbB signaling network. Nat Rev Mol Cell Biol 2001;2:127-37.
               60.  Hopkins CR, Miller K, Beardmore JM. Receptor-mediated endocytosis of transferrin and epidermal growth factor receptors: a comparison
                   of constitutive and ligand-induced uptake. J Cell Sci Supp 1985;3:173-86.
               61.  Sorkin A, Goh LK. Endocytosis and intracellular trafficking of ErbBs. Exp Cell Res 2008;314:3093-106.
               62.  Roepstorff K, Grandal MV, Henriksen L, Knudsen SL, Lerdrup M, et al. Differential effects of EGFR ligands on endocytic sorting of the
                   receptor. Traffic 2009;10:1115-27.
               63.  Willmarth NE, Baillo A, Dziubinski ML, Wilson K, Riese DJ 2nd, et al. Altered EGFR localization and degradation in human breast cancer
                   cells with an amphiregulin/EGFR autocrine loop. Cell Signal 2009;21:212-9.
               64.  Haigler HT, McKanna JA, Cohen S. Rapid stimulation of pinocytosis in human carcinoma cells A-431 by epidermal growth factor. J Cell
                   Biol 1979;83:82-90.
               65.  Hanawa M, Suzuki S, Dobashi Y, Yamane T, Kono K, et al. EGFR protein overexpression and gene amplification in squamous cell
                   carcinomas of the esophagus. Int J Cancer 2006;118:1173-80.
               66.  Vieira AV, Lamaze C, Schmid SL. Control of EGF receptor signaling by clathrin-mediated endocytosis. Science 1996;274:2086-9.
               67.  Garay C, Judge G, Lucarelli S, Bautista S, Pandey R, et al. Epidermal growth factor-stimulated Akt phosphorylation requires clathrin or
                   ErbB2 but not receptor endocytosis. Mol Biol Cell 2015;26:3504-19.
               68.  Wang Y, Pennock S, Chen X, Wang Z. Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways
                   leading to cell survival. Mol Cell Biol 2002;22:7279-90.
               69.  Jorissen RN, Walker F, Pouliot N, Garrett TP, Ward CW, et al. Epidermal growth factor receptor: mechanisms of activation and signalling.
                   Exp Cell Res 2003;284:31-53.
               70.  Sebastian S, Settleman J, Reshkin SJ, Azzariti A, Bellizzi A, et al. The complexity of targeting EGFR signalling in cancer: from expression
                   to turnover. Biochim Biophys Acta 2006;1766:120-39.
               71.   Wiley HS. Trafficking of the ErbB receptors and its influence on signaling. Exp Cell Res 2003;284:78-88.
               72.  Nishimura Y, Takiguchi S, Ito S, Itoh K. EGF-stimulated AKT activation is mediated by EGFR recycling via an early endocytic pathway in
                   a gefitinibresistant human lung cancer cell line. Int J Oncol 2015;46:1721-9.
               73.  Cordenonsi M, Zanconato F, Azzolin L, Forcato M, Rosato A, et al. The Hippo transducer TAZ confers cancer stem cell-related traits on
                   breast cancer cells. Cell 2011;147:759-72.
               74.  Gan Y, Shi C, Inge L, Hibner M, Balducci J, et al. Differential roles of ERK and Akt pathways in regulation of EGFR-mediated signaling
                   and motility in prostate cancer cells. Oncogene 2010;29:4947-58.
               75.  Bellacosa A, de Feo D, Godwin AK, Bell DW, Cheng JQ, et al. Molecular alterations of the AKT2 oncogene in ovarian and breast
                   carcinomas. Int J Cancer 1995;64:280-5.
               76.  Sun M, Wang G, Paciga JE, Feldman RI, Yuan ZQ, et al. AKT1/PKBα kinase is frequently elevated in human cancers and its constitutive
                   activation is required for oncogenic transformation in NIH3T3 cells. Am J Pathol 2001;159:431-7.
               77.  Ringel MD, Hayre N, Saito J, Saunier B, Schuppert F, et al. Overexpression and overactivation of Akt in thyroid carcinoma. Cancer Res
                   2001;61:6105-11.
               78.  Sheng Q, Liu J. The therapeutic potential of targeting the EGFR family in epithelial ovarian cancer. Br J Cancer 2011;104:1241-5.
               79.  Meng Q, Xia C, Fang J, Rojanasakul Y, Jiang BH. Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and
                   proliferation through the p70S6K1 pathway. Cell Signal 2006;18:2262-71.
               80.  Sainsbury JR, Farndon JR, Needham GK, Malcolm AJ, Harris AL. Epidermal-growth-factor receptor status as predictor of early recurrence
                   of and death from breast cancer. Lancet 1987;1:1398-402.
               81.  Schiff BA, McMurphy AB, Jasser SA, Younes MN, Doan D, et al. Epidermal growth factor receptor (EGFR) is overexpressed in anaplastic
                   thyroid cancer, and the EGFR inhibitor gefitinib inhibits the growth of anaplastic thyroid cancer. Clin Cancer Res 2004;10:8594-602.
               82.  Hyatt DC, Ceresa BP. Cellular localization of the activated EGFR determines its effect on cell growth in MDA-MB-468 cells. Exp Cell Res
                   2008;314:3415-25.
               83.  Wang YN, Lee HH, Lee HJ, Du Y, Yamaguchi H, et al. Membrane-bound trafficking regulates nuclear transport of integral epidermal
                   growth factor receptor (EGFR) and ErbB-2. J Biol Chem 2012;287:16869-79.
               84.  Wang YN, Wang H, Yamaguchi H, Lee HJ, Lee HH, et al. COPI-mediated retrograde trafficking from the Golgi to the ER regulates EGFR
                   nuclear transport. Biochem Biophys Res Commun 2010;399:498-504.
               85.  Du Y, Shen J, Hsu JL, Han Z, Hsu MC, et al. Syntaxin 6-mediated Golgi translocation plays an important role in nuclear functions of EGFR
                   through microtubule-dependent trafficking. Oncogene 2014;33:756-70.
               86.  Liao HJ, Carpenter G. Role of the Sec61 translocon in EGF receptor trafficking to the nucleus and gene expression. Mol Biol Cell
                   2007;18:1064-72.
               87.  Lo HW, Ali-Seyed M, Wu Y, Bartholomeusz G, Hsu SC, et al. Nuclear-cytoplasmic transport of EGFR involves receptor endocytosis,
                   importin beta1 and CRM1. J Cell Biochem 2006;98:1570-83.
               88.  Hanada N, Lo HW, Day CP, Pan Y, Nakajima Y, et al. Co-regulation of B-Myb expression by E2F1 and EGF receptor. Mol Carcinog
                   2006;45:10-7.
               89.  Lo HW, Hsu SC, Ali-Seyed M, Gunduz M, Xia W, et al. Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO
                   pathway. Cancer Cell 2005;7:575-89.
               90.  Lo HW, Xia W, Wei Y, Ali-Seyed M, Huang SF, et al. Novel prognostic value of nuclear epidermal growth factor receptor in breast cancer.
                   Cancer Res 2005;65:338-48.
               91.  Ortega J, Li JY, Lee S, Tong D, Gu L, et al. Phosphorylation of PCNA by EGFR inhibits mismatch repair and promotes misincorporation
                   during DNA synthesis. Proc Natl Acad Sci U S A 2015;112:5667-72.
               92.  Saloura V, Vougiouklakis T, Zewde M, Deng X, Kiyotani K, et al. WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic
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