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Maitland                                                                                                                                                                           Prostate cancer: from bench to bedside

               Trombetta JJ, Lu D, Tallapragada N, Tahirova N, Kim S, Blumenstiel   L, Morris MJ, Danila DC, Humm J, Larson S, Fleisher M, Sawyers
               B, Sougnez C, Lowe  A,  Wong B,  Auclair D,  Van  Allen EM,   CL;  Prostate  Cancer Foundation/Department  of Defense  Prostate
               Nakabayashi M, Lis RT, Lee GS, Li T, Chabot MS, Ly A, Taplin ME,   Cancer Clinical Trials Consortium. Antitumour activity of MDV3100
               Clancy TE, Loda M, Regev A, Meyerson M, Hahn WC, Kantoff PW,   in castration-resistant prostate cancer:  a phase 1-2 study.  Lancet
               Golub TR, Getz G, Boehm JS, Love JC. Whole-exome sequencing   2010;375:1437-46.
               of circulating tumor cells provides a window into metastatic prostate   21.  Higano CS, Beer TM, Taplin ME, Efstathiou E, Hirmand M, Forer D,
               cancer. Nat Biotechnol 2014;32:479-84.            Scher HI. Long-term safety and antitumor activity in the phase 1-2
           13.  Beltran H, Rickman DS, Park K, Chae SS, Sboner A, MacDonald TY,   study of enzalutamide in pre- and post-docetaxel castration-resistant
               Wang Y, Sheikh KL, Terry S, Tagawa ST, Dhir R, Nelson JB, de la   prostate cancer. Eur Urol 2015;68:795-801.
               Taille A, Allory Y, Gerstein MB, Perner S, Pienta KJ, Chinnaiyan AM,   22.  Butler DE, Marlein C, Walker HF, Frame FM, Mann VM, Simms MS,
               Wang Y, Collins CC, Gleave ME, Demichelis F, Nanus DM, Rubin   Davies BR, Collins AT, Maitland NJ. Inhibition of the PI3K/AKT/
               MA. Molecular  characterization  of neuroendocrine  prostate  cancer   mTOR pathway activates  autophagy and compensatory Ras/Raf/
               and identification of new drug targets. Cancer Discov 2011;1:487-95.  MEK/ERK signalling in prostate cancer. Oncotarget 2017;8:56698-
           14.  Beltran H, Prandi D, Mosquera JM, Benelli  M, Puca L, Cyrta J,   713.
               Marotz C, Giannopoulou E, Chakravarthi BV, Varambally S, Tomlins   23.  Ulukaya E, Frame FM, Cevatemre B, Pellacani D, Walker H, Mann
               SA, Nanus DM, Tagawa ST, Van Allen EM, Elemento O, Sboner A,   VM, Simms MS, Stower MJ, Yilmaz VT, Maitland NJ. Differential
               Garraway LA, Rubin MA, Demichelis F. Divergent clonal evolution   cytotoxic activity of a novel palladium-based compound on prostate
               of castration-resistant neuroendocrine  prostate  cancer.  Nat Med   cell  lines,  primary  prostate  epithelial  cells  and prostate  stem  cells.
               2016;22:298-305.                                  PLoS One 2013;8:e64278.
           15.  Horoszewicz JS, Leong SS,  Chu  TM,  Wajsman ZL, Friedman M,   24.  Rane JK, Droop  AP, Maitland  NJ.  A detailed  analysis of gene
               Papsidero L, Kim U,  Chai LS, Kakati S, Arya SK,  Sandberg AA.   expression in human basal, luminal, and stromal cell populations from
               The LNCaP cell line -- a new model for studies on human prostatic   benign prostatic  hyperplasia  tissues and comparisons with cultured
               carcinoma. Prog Clin Biol Res 1980;37:115-32.     basal cells. Eur Urol 2017;72:157-9.
           16.  Tran C, Ouk S, Clegg NJ, Chen Y, Watson PA, Arora V, Wongvipat J,   25.  Berthon P, Cussenot O, Hopwood L, Leduc A, Maitland N. Functional
               Smith-Jones PM, Yoo D, Kwon A, Wasielewska T, Welsbie D, Chen   expression  of  sv40 in  normal  human  prostatic  epithelial  and
               CD, Higano CS, Beer TM, Hung DT, Scher HI, Jung ME, Sawyers   fibroblastic cells - differentiation pattern of nontumorigenic cell-lines.
               CL. Development of a second-generation antiandrogen for treatment   Int J Oncol 1995;6:333-43.
               of advanced prostate cancer. Science 2009;324:787-90.  26.  Sobel RE,  Wang  Y, Sadar MD. Molecular analysis and
           17.  Saad  F.  Evidence  for  the  efficacy  of  enzalutamide  in   characterization of PrEC, commercially available prostate epithelial
               postchemotherapy metastatic castrate-resistant prostate cancer. Ther   cells. In Vitro Cell Dev Biol Anim 2006;42:33-9.
               Adv Urol 2013;5:201-10.                        27.  Centenera MM, Raj GV, Knudsen KE, Tilley WD, Butler LM. Ex vivo
           18.  Merseburger AS, Haas GP, von Klot CA. An update on enzalutamide   culture of human prostate tissue and drug development. Nat Rev Urol
               in the treatment of prostate cancer. Ther Adv Urol 2015;7:9-21.  2013;10:483-7.
           19.  Cicero G, DE Luca R, Dorangricchia P, Dieli F. The clinical efficacy   28.  Fox EJ, Reid-Bayliss KS, Emond MJ, Loeb LA. Accuracy of next
               of enzalutamide  in metastatic  prostate cancer:  prospective  single-  generation sequencing platforms. Next Gener Seq Appl 2014;1: pii:
               center study. Anticancer Res 2017;37:1475-80.     1000106.
           20.  Scher HI, Beer TM, Higano CS, Anand A, Taplin ME, Efstathiou E,   29.  Gawad C, Koh W, Quake SR. Single-cell genome sequencing: current
               Rathkopf D, Shelkey J, Yu EY, Alumkal J, Hung D, Hirmand M, Seely   state of the science. Nat Rev Genet 2016;17:175-88.


































            270                                                             Journal of Cancer Metastasis and Treatment ¦ Volume 3 ¦ November 17, 2017
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