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Page 6 of 13                                              Jiang et al. Hepatoma Res 2020;6:52  I  http://dx.doi.org/10.20517/2394-5079.2020.47

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               Figure 2. Age-standardised and overall 5-year relative survival rates of primary liver cancer in some selected countries during 1974-
               2016. A: Age-standardised 5-year relative survival rates (a: Europe *[17,19,35,36] ; b: other regions [27,28,30,31] ); B: overall 5-year relative
               survival rates (a: Europe [14,16,19,21,22,33-35] ; b: Asia [6-12,25,26] ; c: North America [11,12,14,15,29-32] ; d: Africa [37,38] ). *The divisions of Europe refer to the
               EUROCARE report


               Liver cancer survival in China
               Table 3 shows the details of the population-based overall and age-standardized 5-year RSRs of PLC in some
                                                                                               [39]
                                                                                    [45]
                                                                           [46]
               areas in China. It mainly includes the survival of PLC in the nation , Beijing , Shanghai , Zhejiang
                                          [28]
                       [41]
                                                                [28]
                                                   [47]
                                                                                                       [48]
               Province , Liaoning Province , Taiwan , Hong Kong , Haining and Jiashan (Zhejiang Province) ,
                                                                 [51]
               Cixian (Hebei Province) [49,50] , Huaian (Jiangsu Province) , Qidong (Jiangsu Province) [40,52] , and Jintan
                                                  [53]
               district (Changzhou, Jiangsu Province) . Among them, cases of DCO were explicitly excluded in the
               reports of Shanghai , Qidong of Jiangsu , Haining, and Jiashan of Zhejiang , and Liaoning .
                                                                                 [48]
                                                  [40]
                                [39]
                                                                                               [28]
               As shown in Table 3, the 5-year RSRs of PLC improved gradually over time. The age-standardized 5-year
               RSRs of liver cancer patients in China (2003-2015) are lower than that of Korea and Japan for a similar time
               period. For the overall 5-year RSRs, gender difference was not found in our review as the survival rates of
               liver cancer in women were not consistently higher than that in men. The highest overall 5-year RSR of
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