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Jiang et al. Hepatoma Res 2020;6:52  I  http://dx.doi.org/10.20517/2394-5079.2020.47                                             Page 5 of 13

               Table 2. Population-based sex-specific age-standardised 5-year relative survival rates of primary liver cancer in selected
               countries
                                                                       Age-standardised 5-year RSR (%)
                Region                          Year
                                                                      Male                  Female
                Singapore [13]                1968-1972                5.0                   3.0
                                              1973-1977                1.0                   6.0
                                              1978-1982                3.0                   8.0
                                              1983-1987                2.0                   3.0
                                              1988-1992                3.0                   2.0
                Europe [16]                   1990-1994                6.2                   6.7
                Austria [16]                  1990-1994                7.0                   -
                Czech Republic [16]           1990-1994                1.1                   3.4
                Denmark [16,23,24]            1989-1993                3.0                   3.0
                                              1990-1994                -                     2.3
                                              1994-1998                4.0                   4.0
                                              1999-2003                3.0                   5.0
                England [16]                  1990-1994                6.1                   7.2
                Estonia [16]                  1990-1994                5.5                   -
                Finland [16,23,24]            1989-1993                4.0                   5.0
                                              1990-1994                3.9                   4.4
                                              1994-1998                7.0                   7.0
                                              1999-2003                8.0                   8.0
                Iceland [23,24]               1989-1993                14.0                  -
                                              1994-1998                7.0                   -
                                              1999-2003                7.0                   -
                France [16,19]                1989-1997                8.0                   9.0
                                              1990-1994                6.9                   -
                Germany [16]                  1990-1994                -                     3.8
                Italy [16]                    1990-1994                6.2                   8.6
                The Netherlands  [16]         1990-1994                6.2                   5.8
                Norway [16,23,24]             1989-1993                6.0                   8.0
                                              1990-1994                2.1                   3.2
                                              1994-1998                5.0                   11.0
                                              1999-2003                5.0                   11.0
                Poland [16]                   1990-1994                -                     1.3
                Scotland [16]                 1990-1994                -                     4.8
                Slovakia [16]                 1990-1994                -                     1.8
                Slovenia [16]                 1990-1994                -                     4.9
                Spain [16]                    1990-1994                10.4                  11.6
                Sweden [16,23,24]             1989-1993                5.0                   3.0
                                              1990-1994                2.9                   3.1
                                              1994-1998                6.0                   7.0
                                              1999-2003                7.0                   8.0
                Switzerland [16]              1990-1994                5.9                   -
                Wales [16]                    1990-1994                5.1                   6.3
               -: No reports or non-available in the original articles; RSR: relative survival rate

                                                                                          [11]
                                                                      [26]
               the age-specific 5-year RSRs from Europe [16,17,36] , USA , Japan , Canada [30,31] , Korea , and China [39-41]
                                                              [15]
               in the period between 1990-2010. The 5-year RSRs decreased with age. The rates of patients aged 15-44,
               followed by those aged 45-54, were higher than other age groups, while the prognosis of patients aged 75
                                                                                            [30]
               or older was poor. In the age groups of 35-44 and 45-54, the rate in Canada (2004-2006)  was markedly
                                                                                           [11]
               higher than that in other regions. In the age 65-74 group, the rate of Korea (2006-2010)  was markedly
               higher than that in other regions, and that in those age 75 or older, was highest in the Zhejiang Province
                         [41]
               (2005-2010)  of China compared to other regions or countries. Of note however, some reports estimate
               RSRs after excluding DCO and autopsy cases [11-14,18,21,22,24,26,28,30,31,35,36,39,40,42-45] .
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