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Table 3. Overall response according to Modified Response Evaluation Criteria In Solid Tumors for hepatocellular carcinoma
Target lesions Nontarget lesions New lesions Overall response
CR CR No CR
CR IR/SD No PR
PR Non-PD No PR
SD Non-PD No SD
PD Any Yes or no PD
Any PD Yes or no PD
Any Any Yes PD

CR: complete response; PR: partial response; SD: stable disease; PD: progressive disease; IR: incomplete response

DECLARATIONS
Authors’ contributions
Conception of the work,drafting and revisingthe work: de Santis A, Gallusi G

Availability of data and materials
Not applicable.

Financial support and sponsorship
None.

Conflicts of interest
All authors declared that there are no conflicts of interest.

Ethical approval and consent to participate
Not applicable.

Consent for publication
Not applicable.

Copyright
© The Author(s) 2019.

REFERENCES
1. Bréchot C, Jaffredo F, Lagorce D, Gerken G, Meyer zum Büschenfelde K, et al. Impact of HBV, HCV and GBV-C/HGV on
hepatocellular carcinomas in Europe: results of a European concerted action. J Hepatol 1998;29:173-83.
2. Smith R. Screening fundamentals. J Natl Cancer Inst Monogr 1997;(22):15-9.
3. Bruix J, Sherman M; American Association for the Study of Liver Diseases. Management of hepatocellular carcinoma: an update.
Hepatology 2011;53:1020-2.
4. European Association For The Study Of The Liver; European Organisation For Research And Treatment Of Cancer. EASL-EORTC
clinical practice guidelines: management of hepatocellular carcinoma. J Hepatol 2012;56:908-43.
5. Heimbach JK, Kulik LM, Finn RS, Sirlin CB, Abecassis MM, et al. AASLD guidelines for the treatment of hepatocellular carcinoma.
Hepatology 2018;67:358-80.
6. Bennett GL, Krinsky GA, Abitbol RJ, Kim SY, Theise ND, et al. Sonographic detection of hepatocellular carcinoma and dysplastic
nodules in cirrhosis: correlation of pretransplantation sonography and liver explant pathology in 200 patients. AJR Am J Roentgenol
2002;179:75-80.
7. Bolondi L. Screening for hepatocellular carcinoma in cirrhosis. J Hepatol 2003;39:1076-84.
8. Nowicki TK, Markiet K, Szurowska E. Diagnostic imaging of hepatocellular carcinoma - a pictorial essay. Curr Med Imaging Rev
2017;13:140-53.
9. Kudo M, Izumi N, Kokudo N, Matsui O, Sakamoto M, et al. Management of hepatocellular carcinoma in Japan: consensus-based
clinical practice guidelines proposed by the Japan Society of Hepatology (JSH) 2010 updated version. Dig Dis 2011;29:339-64.
10. Omata M, Lesmana LA, Tateishi R, Chen PJ, Lin SM, et al. Asian Pacific Association for the Study of the Liver consensus
recommendations on hepatocellular carcinoma. Hepatol Int 2010;4:439-74.
11. Russo FP, Imondi A, Lynch EN, Farinati F. When and how should we perform a biopsy for HCC in patients with liver cirrhosis in