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Ban et al. Hepatoma Res 2021;7:13 I http://dx.doi.org/10.20517/2394-5079.2020.104 Page 7 of 8

be the reverse of the order. The hepatic vein has often been used as an indicator of hepatic dissection in
anatomical liver resection. However, since anatomical liver resection is performed in the vascular supply
area of the portal vein, hepatic vein-guided liver resection may not be synonymous with anatomical
resection. In addition, a hepatectomy method using the hepatic vein as a guide has been proposed until
now, but the terms have not been unified. In the future, it will be important to demonstrate the usefulness
of this technique for hepatectomy using the hepatic vein as a reference point. Also, the terminology for
the approach is not entirely consistent. Therefore, it is expected that these procedures will be discussed at
consensus conferences in the future.

CONCLUSION
It should be recognized that the hepatic vein provides a useful structure to guide liver transection for
LLR. It is also an anatomical landmark, to a lesser extent, in open hepatectomy. In the planning of hepatic
transection, it is recommended that the hepatic vein be utilized as the boundary of the transection or a
landmark that serves as an anatomical reference point.

DECLARATIONS
Authors’ contributions
Manuscript writing and operator of LLR: Ban D
Substantial contributions to conception: Esaki M, Shimada K
Technical supports and interpretation: Nara S, Takemoto T
Performed data acquisition, and drawing the figures: Mizui T, Yoshino J

Availability of data and materials
Not applicable.

Financial support and sponsorship
None.

Conflicts of interest
All authors declared that there are no conflicts of interest.

Ethical approval and consent to participate
Not applicable.

Consent for publication
Not applicable.

Copyright
© The Author(s) 2021.

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