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Page 28 of 54 Yang et al. Chem Synth 2023;3:7 https://dx.doi.org/10.20517/cs.2022.38
Scheme 35. 3-Olefinic oxindoles as lactone construction reagents 66 in Michael-initiated Pinnick oxidative spirolactonization reactions.
[92]
This figure is used with permission from the American Chemical Society .
Scheme 36. Spirolactonization reaction of 3-hydroxyoxindoles 69 for construction of chiral spirolactones.
Scheme 37. Spirolactonization reaction of 3-hydroxyoxindoles 69 and olefinic azlactones 70. This figure is used with permission from
[95]
the American Chemical Society .
With DBU as the catalyst, various spirocyclic butyrolactone-oxindoles 71 were successfully isolated in high
