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REFERENCES
1. Nitiss JL. Investigating the biological functions of DNA topoisomerases in eukaryotic cells. Biochim Biophys Acta 1998;1400:63-81.
2. Wang JC. Cellular roles of DNA topoisomerases: a molecular perspective. Nat Rev Mol Cell Biol 2002;3:430-40.
3. Nakasu S, Kikuchi A. Reverse gyrase; ATP-dependent Type I topoisomerase from Sulfolobus. EMBO J 1985;4:2705-10.
4. Tse-Dinh YC. Bacterial and archeal Type I topoisomerases. Biochim Biophys Acta 1998;1400:19-27.
5. Seki T, Seki M, Katada T, Enomoto T. Isolation of a cDNA encoding mouse DNA topoisomerase III which is highly expressed at the
mRNA level in the testis. Biochim Biophys Acta 1998;1396:127-31.
6. Slesarev AI, Belova GI, Lake JA, Kozyavkin SA. Topoisomerase V from Methanopyrus kandleri. Methods Enzymol 2001;334:179-92.
7. Liu LF, Wang JC. Supercoiling of the DNA template during transcription. Proc Natl Acad Sci U S A 1987;84:7024-7.
8. Sissi C, Palumbo M. Effects of magnesium and related divalent metal ions in topoisomerase structure and function. Nucleic Acids Res
2009;37:702-11.
9. Cuya SM, Bjornsti MA, van Waardenburg RCAM. DNA topoisomerase-targeting chemotherapeutics: what’s new? Cancer Chemother
Pharmacol 2017;80:1-14.
10. Sekiguchi J, Shuman S. Site-specific ribonuclease activity of eukaryotic DNA topoisomerase I. Mol Cell 1997;1:89-97.
11. Champoux JJ. DNA topoisomerases: structure, function, and mechanism. Annu Rev Biochem 2001;70:369-413.
12. Pommier Y. Topoisomerase I inhibitors: camptothecins and beyond. Nat Rev Cancer 2006;6:789-802.
13. Champoux JJ. Domains of human topoisomerase I and associated functions. Prog Nucleic Acid Res Mol Biol 1998;60:111-32.
14. Stewart L, Ireton GC, Champoux JJ. Reconstitution of human topoisomerase I by fragment complementation. J Mol Biol
1997;269:355-72.
15. Redinbo MR, Stewart L, Champoux JJ, Hol WG. Structural flexibility in human topoisomerase I revealed in multiple non-isomorphous
crystal structures. J Mol Biol 1999;292:685-96.
16. Stewart L, Redinbo MR, Qiu X, Hol WG, Champoux JJ. A model for the mechanism of human topoisomerase I. Science
1998;279:1534-41.
17. Wang Z, D’Annessa I, Tesauro C, Croce S, Ottaviani A, et al. Mutation of Gly717Phe in human topoisomerase 1B has an effect on
enzymatic function, reactivity to the camptothecin anticancer drug and on the linker domain orientation. Biochim Biophys Acta
2015;1854:860-8.
18. Stewart L, Ireton GC, Champoux JJ. The domain organization of human topoisomerase I. J Biol Chem 1996;271:7602-8.
19. Redinbo MR, Stewart L, Kuhn P, Champoux JJ, Hol WG. Crystal structures of human topoisomerase I in covalent and noncovalent
complexes with DNA. Science 1998;279:1504-13.
20. Redinbo MR, Champoux JJ, Hol WG. Novel insights into catalytic mechanism from a crystal structure of human topoisomerase I in
complex with DNA. Biochemistry 2000;39:6832-40.
21. Laco GS, Pommier Y. Role of a tryptophan anchor in human topoisomerase I structure, function and inhibition. Biochem J
2008;411:523-30.
22. Albor A, Kaku S, Kulesz-Martin M. Wild-type and mutant forms of p53 activate human topoisomerase I: a possible mechanism for
gain of function in mutants. Cancer Res 1998;58:2091-4.
23. Bharti AK, Olson MOJ, Kufe DW, Rubin EH. Identification of a nucleolin binding site in human topoisomerase I. J Biol Chem
1996;271:1993-7.
24. Simmons DT, Melendy T, Usher D, Stillman B. Simian virus 40 large T antigen binds to topoisomerase. Virology 1996;222:365-74.
25. Madden KR, Stewart L, Champoux JJ. Preferential binding of human topoisomerase I to superhelical DNA. EMBO J 1995;14:5399-409.
26. Schoeffler AJ, Berger JM. DNA topoisomerases: harnessing and constraining energy to govern chromosome topology. Q Rev Biophys
2008;41:41-101.
27. Woo MH, Losasso C, Guo H, Pattarello L, Benedetti P, et al. Locking the DNA topoisomerase I protein clamp inhibits DNA rotation
and induces cell lethality. Proc Natl Acad Sci U S A 2003;100:13767-72.
28. Coletta A, Desideri A. Role of the protein in the DNA sequence specificity of the cleavage site stabilized by the camptothecin
topoisomerase IB inhibitor: a metadynamics study. Nucleic Acids Res 2013;41:9977-86.
29. Siu FM, Pommier Y. Sequence selectivity of the cleavage sites induced by topoisomerase I inhibitors: a molecular dynamics study.
Nucleic Acids Res 2013;41:10010-9.