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Page 20 of 25 Han et al. Cancer Drug Resist 2024;7:16 https://dx.doi.org/10.20517/cdr.2024.01
Figure 10. IsocuB inhibits tumor growth in nude mice. (A) Bossing of the mass in nude mice: the control group is shown above, and the
treatment group is shown below; (B) Bossing: control group at the top and treatment group at the bottom; (C) Body weight changes in
**
nude mice; (D) Daily tumor volume changes after administration ( P < 0.01, **** P < 0.0001 vs. control group); (E) The bossing weight
( **** P < 0.0001 vs. control group); (F) Bossing weight/body weight ( **** P < 0.0001 vs. control group). IsocuB: Isocucurbitacin B.
binding affinity for the top five genes, implying its potential in the growth of glioma through the action of
these genes, which should be further analyzed and investigated. In this study, we analyzed the potential
targets and related pathways of isocuB from a network pharmacology perspective.
