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Saadi et al. Vessel Plus 2020;4:41 Vessel Plus
DOI: 10.20517/2574-1209.2020.54

Review Open Access

Routine use of cerebral protection devices during
transcatheter aortic valve implantation: what does

the evidence say?

Eduardo Keller Saadi , Rodrigo Petersen Saadi , Ana Paula Tagliari 2,3,4 , Maurizio Taramasso 4
1,2
1,3
1 Cardiac Surgery Department, Hospital de Clínicas de Porto Alegre, Porto Alegre 90035-007, Brazil.
2 Cardiac Surgery Department, Hospital São Lucas da PUC-RS, Porto Alegre 90610-000, Brazil.
3 Postgraduate Program in Cardiology and Cardiovascular Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre
90035007, Brazil.
4 Cardiac Surgery Department, University Hospital of Zurich, University of Zurich, Zurich 8091, Switzerland.

Correspondence to: Prof. Eduardo Keller Saadi, Cardiac Surgery Department, Hospital São Lucas da PUC-RS, Avenida Ipiranga,
6690, Porto Alegre 90610-000, Brazil. E-mail: esaadi@terra.com.br

How to cite this article: Saadi EK, Saadi RP, Tagliari AP, Taramasso M. Routine use of cerebral protection devices during
transcatheter aortic valve implantation: what does the evidence say? Vessel Plus 2020;4:41.
http://dx.doi.org/10.20517/2574-1209.2020.54

Received: 9 Oct 2020 First Decision: 9 Nov 2020 Revised: 14 Nov 2020 Accepted: 20 Nov 2020 Published: 18 Dec 2020
Received: First Decision: Revised: Accepted: Published: x
Academic Editor: Frank W. Sellke Copy Editor: Cai-Hong Wang Production Editor: Jing Yu
Science Editor: Copy Editor: Production Editor: Jing Yu

Abstract
Transcatheter aortic valve implantation (TAVI) is a well-established treatment for symptomatic severe aortic
stenosis in intermediate and high-risk patients. However, as TAVI indications increase, concerns regarding adverse
events and complications rise in the same proportion. Stroke is one of the most feared TAVI complications and a
hard endpoint present in all TAVI studies. TAVI-related stroke incidence becomes even more relevant with TAVI
indications spreading to younger, low/intermediate-risk patients. Several devices have been developed to prevent
this catastrophic event, some of them being broadly used. Nevertheless, the evidence for routine use of cerebral
embolic protection devices is still controversial.

Keywords: Transcatheter aortic valve replacement, transcatheter aortic valve implantation, cerebral protection
device, cerebral protection system, Sentinel Cerebral Protection System, stroke prevention

© The Author(s) 2020. Open Access This article is licensed under a Creative Commons Attribution 4.0
International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use,
sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long
as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license,
and indicate if changes were made.

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