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or in the inner/outer curve of the aortic annulus (fluoroscopic insets, bottom left). Note that the “C-tab” is
o
loaded 90 clockwise from the “Hat” marker.

Fluoroscopic images depicting deployment of a 26 mm Evolut Pro valve are shown here. Note that the “Hat”
marker is positioned anteriorly in the center of the deployment device (“center front”), with the C-tab seen
at the inner curve of the ascending aorta. Multi-detector computed tomography analyses indicate good
commissural alignment.

DECLARATIONS
Authors’ contributions
Conception and design, analysis and interpretation of data; drafting of the manuscript or revising it
critically for important intellectual content; and final approval of the manuscript submitted: Sengupta A,
Alexis SL, Kovacic JC, Tang GHL

Availability of data and materials
Not applicable.

Financial support and sponsorship
Dr. Jason Kovacic acknowledges research support from the National Institutes of Health (R01HL130423,
R01HL135093, R01HL148167-01A1).

Conflicts of interest
Dr. Tang GHL is a consultant for Medtronic, Abbott Structural Heart, and W. L. Gore & Associates. All
other authors declared that there are no conflicts of interest.

Ethical approval and consent to participate
Not applicable.

Consent for publication
Not applicable.

Copyright
© The Author(s) 2020.

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