Page 176 - Read Online

Dastidar et al. Vessel Plus 2020;4:14 I http://dx.doi.org/10.20517/2574-1209.2019.36 Page 23 of 29

Lab Invest 2006;86:767-80.
6. Hashizume H, Baluk P, Morikawa S, McLean JW, Thurston G, et al. Openings between defective endothelial cells explain tumor vessel
leakiness. Am J Pathol 2000;156:1363-80.
7. McDonald DM, Baluk P. Significance of blood vessel leakiness in cancer. Cancer Res 2002;62:5381-5.
8. Liao D, Johnson RS. Hypoxia: a key regulator of angiogenesis in cancer. Cancer Metastasis Rev 2007;26:281-90.
9. Kenneth NS, Rocha S. Regulation of gene expression by hypoxia. Bio Chem J 2008;414:19-29.
10. Liu QL, Liang QL, Li ZY, Zhou Y, Ou WT, et al. Function and expression of prolyl hydroxylase 3 in cancers. Arch Med Sci 2013;9:589-93.
11. Koh MY, Darnay BG, Powis G. Hypoxia-associated factor, a novel E3-ubiquitin ligase, binds and ubiquitinates hypoxia-inducible factor
1alpha, leading to its oxygen-independent degradation. Mol Cell Biol 2008;28:7081-95.
12. Buckley DL, Van Molle I, Gareiss PC, Tae HS, Michel J, et al. Targeting the von Hippel-Lindau E3 ubiquitin ligase using small molecules
to disrupt the VHL/HIF-1α interaction. J Am Chem Soc 2012;134:4465-8.
13. Abboud MI, McAllister TE, Leung IKH, Chowdhury R, Jorgensen C, et al. 2-Oxoglutarate regulates binding of hydroxylated hypoxia-
inducible factor to prolyl hydroxylase domain 2. Chem Commun (Camb) 2018;54:3130-3.
14. Mandl M, Depping R. Hypoxia-inducible aryl hydrocarbon receptor nuclear translocator (ARNT) (HIF-1β): is it a rare exception? Mol
Med 2014;20:215-20.
15. Arany Z, Huang LE, Eckner R, Bhattacharya S, Jiang C, et al. An essential role for p300/CBP in the cellular response to hypoxia. Proc
Natl Acad Sci U S A 1996;93:12969-73.
16. Van Hove CE, Van der Donckt C, Herman AG, Bult H, Fransen P. Vasodilator efficacy of nitric oxide depends on mechanisms of
intracellular calcium mobilization in mouse aortic smooth muscle cells. Br J Pharmacol 2009;158:920-30.
17. Pereira KM, Chaves FN, Viana TS, Carvalho FS, Costa FW, et al. Oxygen metabolism in oral cancer: HIF and GLUTs (Review). Oncol
Lett 2013;6:311-6.
18. Chaneton B, Gottlieb E. PGAMgnam style: a glycolytic switch controls biosynthesis. Cancer Cell 2012;22:565-6.
19. Ye F, Chen Y, Xia L, Lian J, Yang S. Aldolase A overexpression is associated with poor prognosis and promotes tumor progression by the
epithelial-mesenchymal transition in colon cancer. Biochem Biophys Res Commun 2018;497:639-45.
20. Michelakis ED, Gurtu V, Webster L, Barnes G, Watson G, et al. Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial
hypertension in genetically susceptible patients. Sci Transl Med 2017;9:eaao4583.
21. Ahmad SS, Glatzle J, Bajaeifer K, Bühler S, Lehmann T, et al. Phosphoglycerate kinase 1 as a promoter of metastasis in colon cancer. Int
J Oncol 2013;43:586-90.
22. Skuli N, Liu L, Runge A, Wang T, Yuan L, et al. Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular
function and tumor angiogenesis. Blood 2009;114:469-77.
23. Takagi H, Koyama S, Seike H, Oh H, Otani A, et al. Potential role of the angiopoietin/tie2 system in ischemia-induced retinal
neovascularization. Invest Ophthalmol Vis Sci 2003;44:393-402.
24. Zhang L, Yang N, Park JW, Katsaros D, Fracchioli S, et al. Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2
in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer. Cancer Res 2003;63:3403-12.
25. Gu J, Yamamoto H, Ogawa M, Ngan CY, Danno K, et al. Hypoxia-induced up-regulation of angiopoietin-2 in colorectal cancer. Oncol
Rep 2006;15:779-83.
26. Jain RK. Determinants of tumour blood flow: a review. Cancer Res 1988;48:2641-58.
27. Sevick EM, Jain RK. Measurement of capillary filtration coefficient in a solid tumour. Cancer Res 1991;51:1352-5.
28. Gamble J, Smaje LH, Spencer PD. Filtration coefficient and osmotic reflection coefficient to albumin in rabbit submandibular gland
capillaries. J Physiol 1988;398:15-32.
29. Gerlowski LE, Jain RK. Effect of hyperthermia on microvascular permeability to macromolecules in normal and tumor tissues. Int J
Microcirc Clin Exp 1985;4:363-72.
30. Jain RK. Transport of molecules across tumour vasculature. Cancer Metastasis Rev 1987;6:559-93.
31. Dvorak HF, Nagy JA, Dvorak JT, Dvorak AM. Identification and characterization of the blood vessels of solid tumors that are leaky to
circulating macromolecules. Am J Pathol 1988;133:95-109.
32. Jain RK. Transport of molecules in the tumour interstitium: a review. Cancer Res 1987;47:3039-51.
33. Boucher Y, Baxter LT, Jain RK. Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: implications for therapy. Cancer
Res 1990;50:4478-84.
34. Wiig H, Tveit E, Hultborn R, Reed RK, Weiss L. Interstitial fluid pressure in DMBA-induced rat mammary tumours. Scand J Clin Lab
Invest 1982;42:159-64.
35. Gerlowski LE, Jain RK. Microvascular permeability of normal and neoplastic tissues. Microvasc Res 1986;31:288-305.
36. Khawar IA, Kim JH, Kuh HJ. Improving drug delivery to solid tumors: Priming the tumour microenvironment. J Controll Release
2015;201:78-89.
37. Butler TP, Grantham FH, Gullino PM. Bulk transfer of fluid in the interstitial compartment of mammary tumors. Cancer Res
1975;35:3084-8.
38. Braun RD, Abbas A, Bukhari SO, Wilson W. Hemodynamic parameters in blood vessels in choroidal melanoma xenografts and rat
choroid. Invest Ophthalmol Vis Sci 2002;43:3045-52.
39. Chary SR, Jain RK. Direct measurement of interstitial convection and diffusion of albumin in normal and neoplastic tissues by
fluorescence photobleaching. Proc Natl Acad Sci U S A 1989;86:5385-9.
40. Wiig H, Tenstad O, Iversen PO, Kalluri R, Bjerkvig R. Interstitial fluid: the overlooked component of the tumor microenvironment?