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Page 14 of 21 Carr et al. Vessel Plus 2020;4:12 I http://dx.doi.org/10.20517/2574-1209.2020.01

8% 8% -25% -3% 8% 8% 8% % 79% 79% 71% 64% 64% 64% 57% 57% 50% 43% 43% 43% 36% 36% 36% 29% 29% 29% 29% 29% 29% 29% 29% 29% 29% 21%

8% 8% 8% 8% 8% 8% 8% n = 14 11 11 10 9 9 9 8 8 7 6 6 6 5 5 5 4 4 4 4 4 4 4 4 4 4 3

Long-term models
8% 8% 8% 8% 8% 8% 8%

35
1 1 1 1 1 1 1 Variable Left ventricular function Comb. arterial disease Comb. heart failure variables Peripheral arterial disease Comb. CHF or NYHA Comb. vessel disease Body size measurements Congestive heart failure Comb. any MI variable Comb. critical state

Diffuse/severe disease Comb. HTN or BP Inotropic medication Comb. critical state Comb. PCI variables Total variables (excl. combinations) Age Renal failure Diabetes Lung disease Gender Neurologic disease Left main disease Urgency Repeat operation History of MI Hypertension Comb. HTN or BP Race or ethnicity Smoking status Cardiogenic shock NYHA class

Active MI Type of graft(s) % 91% 69% 61% 60% 59% 57% 57% 57% 51% 51% 49% 48% 48% 45% 41% 37% 35% 31% 31% 29% 28% 27% 24% 23% 20% 20%

n= 75 68 52 46 45 44 43 43 43 38 38 37 36 36 34 31 28 26 23 23 22 21 20 18 17 15 15
11%

Short-term models
11%

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1 Δa: change from < 1998; Δb: change from 1998-2007. Comb: combination variable; CHF: congestive heart failure; NYHA: New York Heart Association; MI: myocardial infarction; ECG: electrocardiogram; IABP: intra-aortic baloon pump; HTN: hypertension; BP: blood pressure; PCI: percutaneous coronary intervention; PTCA: percutaneous transluminal coronary angioplasty; CPR: cardiopulmonary Variable Comb. heart failure variables Peripheral arter

Preoperative thrombolysis Total variables (excl. combinations) resuscitation; ASA: American Society of Anethesiology; ACE: angiotensin converting enzyme; INR: international normalized ratio; PT: prothromin time % Age 89% Left ventricular function 70% Urgency 61% Gender 58% Repeat operation 58% Renal failure 57% Comb. arterial disease 56% 54% History of MI 51% Comb. any MI variable 49% 47% Comb. CHF or NYHA 47% Comb. critical state

n = 89 79 62 54 52 52 51 50 48 45 44 42 42 41 40 37 37 32 28 27 27 26 23 21 19 19 19
Table 5. Models containing only preoperative data

Left ventricular function Comb. arterial disease Comb. heart failure variables Peripheral arterial disease Comb. CHF or NYHA Comb. any MI variable Comb. critical state Comb. vessel disease Neurologic disease Congestive heart failure Cardiogenic shock Body size measurements Number of diseased vessels Comb. HTN or BP Comb. ECG or arrhythmia variables

All models Variable Age Renal failure Gender Urgency Repeat operation History of MI Lung disease Diabetes Left main disease NYHA class Hypertension