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Page 16 of 21 Carr et al. Vessel Plus 2020;4:12 I http://dx.doi.org/10.20517/2574-1209.2020.01

0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0%

0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 39

Aortic cross-clamp duration Endocarditis Abdominal aortic aneurysm PTCA failure/emergency Stent thrombosis Any family history variable Antiarrhythmic agents Other ECG abnormalities Non-CABG surgery Anticoagulation or antiplatelet use Preoperative thrombolysis PT or INR Critical state Disaster, catastrophic state Anemia (hemoglobin, hematocrit) Transfusion Refused blood products Preop intubation Concurrent procedure A published comorbidity

3% 1% 1% 1% 1% 1% 1% 1% 1% 1% 1% 1% 1% 1% 1% 1% 1% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0%

2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 75

Preoperative cardiac biomarkers Date or order of surgery Recent admissions Calcified aorta Killip classification Location or type of surgical center Any family history variable Antiarrhythmic agents Non-CABG surgery Preoperative thrombolysis PT or INR Transfusion Serum albumin ACE inhibitor use ASA classification Insurance type or status Acute mental status changes Functional state Number of grafts Type of graft(s) Comb. graft variables

2% 2% 2% 1% 1% 1% 1% 1% 1% 1% 1% 1% 1% 1% 1% 1% 1% 1% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0%

2 2 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 76 angiotensin converting enzyme; INR: international normalized ratio; PT: prothromin time

Preoperative cardiac biomarkers Location or type of surgical center Any family history variable Antiarrhythmic agents Preoperative thrombolysis Insurance type or status Acute mental status changes Cardiopulmonary bypass time Center’s case frequency Aortic cross-clamp duration Abdominal aortic aneurysm Refused blood products Concurrent procedure Other preoperative comorbidities Patient education level/literacy Left ventricular hypertrophy Ti

Steroid use Recent admissions Calcified aorta Killip classification Non-CABG surgery PT or INR Transfusion Serum albumin ACE inhibitor use Functional state ASA classification Number of grafts Type of graft(s) Comb. graft variables Blood pressure Heart rate