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Schiavone et al.                                                                                                                                                           Modelling of metallic and polymeric stents
































           Figure 4: Stress-stretch curves for the three artery layers: Holzapfel-Gasser-Ogden model vs. experimental data [25]
           Mises stress in the Xience and Elixir stents relaxed to   and localized  rupture for plaque  as evidenced  in
           706 MPa and 50 MPa, respectively [Figure 7B]. These   numerous studies. [28,29]  In our case, plaque rupture is
           are also the residual stresses generated in the stent   likely to happen towards the ends of plaque region, a
           after crimping. And the diameter of both stents settled   condition that can lead to heart attack (coronary artery)
           at about 1.5 mm.                                   or stroke (carotid  artery). In addition,  there could  be

           Stent expansion
           Pressure-diameter plots in Figure 8 showed that Elixir
           stent  experienced a  lower rate  of  expansion than
           Xience stent. Both stents developed a saturation state
           in expansion  with the increasing pressure, but Elixir
           stent reached the saturation earlier. At the maximum
           pressure, the stent outer diameter was computed
           as 2.66  mm  and 2.61 mm  for  the Xience and Elixir
           stents, respectively. The recoiling effect was 11% for
           the Xience  stent  [Figure  8B],  which  is  significantly
           lower than that for the Elixir stent (20%; Figure 8B).
           Consequently,  a  larger  final  diameter  was  achieved   Figure 5: Illustration of assembly used in crimping simulation for
           for the Xience stent (2.40 mm) when compared to the   Elixir stent
           Elixir  stent (2.10 mm only). Consistently, the Xience
           stent also showed considerably less dogboning effect
           (24%) than the Elixir stent (45%).

           High levels of stresses were developed in both stents
           following  their deployment  in the artery  [Figure  9].
           Similar to the crimping  process, the maximum von
           Mises stresses were found in the U-bend districts, with
           a value of 935 MPa for the Xience  and 95 MPa for
           the Elixir stent. In the artery, the peak stresses were
           generally found on the  plaque, especially towards
           the ends of the stenosis.  This was caused by the
           dogboning  effect  of  the  implanted stent.  There is   Figure 6: Deformation of Elixir stent and balloon (A) before, (B)
           a direct connection between stress  concentration   during and (C) at the end of the crimping process
             16                                                                                                                      Vessel Plus ¦ Volume 1 ¦ March 31, 2017
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