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Page 6 of 15 Novotny et al. Vessel Plus 2022;6:51 https://dx.doi.org/10.20517/2574-1209.2021.139

MI (%) 5.9 4.6 6.8 0.5677 17.8 18.5 17.2 0.8501
PPM/ICD (%) 9.3 16.1 4.2 0.0038 20.2 26.2 14.1 0.0870
Depression (%) 7.3 5.8 8.5 0.4586 10.9 10.8 10.9 0.9755
Bipolar disorder (%) 1.0 2.3 0.0 0.1782 0.0 0.0 0.0 -
Schizophrenia (%) 0.0 0.0 0.0 - 1.6 0.0 3.1 0.2448
Dementia (%) 0.0 0.0 0.0 - 3.1 4.6 1.6 0.6260
Bicuspid aortic valve (%) 1.0 0.0 1.7 0.5103 0.0 0.0 0.0 -
Syncope (%) 0.5 0.0 0.9 1.0000 0.0 0.0 0.0 -
Dyspnea (%) 3.4 3.5 3.4 1.0000 3.9 4.6 3.1 1.0000
Chest pain (%) 2.4 3.5 1.7 0.6621 2.3 3.1 1.6 1.0000
Hyperlipidemia (%) 53.7 63.2 46.6 0.0184 67.4 69.2 65.6 0.6621
Elevated lipoprotein (%) 0.0 0.0 0.0 - 0.0 0.0 0.0 -
History of mitral valve repair or replacement (%) 19.0 16.1 21.2 0.3583 11.6 13.9 9.4 0.4283
AAA (%) 2.4 2.3 2.5 1.0000 1.5 0.0 3.1 0.2477
Non-rheumatic aortic stenosis (%) 55.6 49.4 60.2 0.1259 64.3 72.3 56.3 0.0569
Rheumatic heart disease (%) 6.8 11.5 3.4 0.0283 8.5 7.7 9.4 0.7322
Obstructive sleep apnea (%) 12.7 8.1 16.1 0.0867 10.9 9.2 12.5 0.5506
Leukemia (%) 0.5 1.2 0.0 0.4244 1.6 3.1 0.0 0.4911
Lymphoma (%) 1.0 1.2 0.9 1.0000 0.8 1.5 0.0 1.0000
CKD with dialysis (%) 1.0 2.3 0.0 0.1810 4.7 4.6 4.7 1.0000
CKD without dialysis (%) 19.0 23.0 16.1 0.2144 39.5 38.5 40.6 0.8016
Iron deficiency anemia (%) 13.7 9.2 17.0 0.1101 13.2 13.9 12.5 0.8212
Rheumatoid arthritis & collagen vascular 3.9 3.5 4.2 1.0000 5.4 3.1 7.8 0.2743
diseases (%)
Fluid & electrolyte disorders (%) 2.0 4.6 0.0 0.0319 0.8 1.5 0.0 1.0000
Pulmonary hypertension (%) 18.1 26.4 11.9 0.0073 22.5 26.2 18.8 0.3139
Thrombocytopenia (%) 31.7 34.5 29.7 0.4634 16.3 16.9 15.6 0.8417
Hypothyroidism (%) 11.7 12.6 11.0 0.7203 19.4 15.4 23.4 0.2473
IABP (%) 3.4 5.8 1.7 0.1327 0.8 0.0 1.6 0.4945
Elixhauser mortality index score 13.60 ± 11.15 15.14 ± 11.02 12.47 ± 11.16 0.0896 14.45 ± 10.55 15.43 ± 10.61 13.45 ± 10.48 0.2888
Elixhauser readmission index score 22.20 ± 14.59 23.67 ± 14.68 21.13 ± 14.49 0.2198 30.52 ± 15.60 30.43 ± 15.45 30.61 ± 15.87 0.9485
r-SAVR: Redo surgical aortic valve replacement; viv-TAVR: valve-in-valve transcatheter aortic valve replacement; AF/AFL: atrial fibrillation/flutter; CHF: congestive heart failure; CAD: coronary artery disease;
COPD: chronic obstructive pulmonary disease; MI: myocardial infarction; PPM: permanent pacemaker; ICD: implantable cardiac defibrillator; AAA: abdominal aortic aneurysm; CKD: chronic kidney disease; IABP:
intra-aortic balloon pump.