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Novotny et al. Vessel Plus 2022;6:51 Vessel Plus
DOI: 10.20517/2574-1209.2021.139
Original Article Open Access
Preoperative atrial fibrillation/flutter impact on risk-
adjusted repeat aortic intervention patients
1
2
3
3
1
1
Samantha Novotny , Julia Dokko , Xiaoyue Zhang , Sohaib Agha , Ashutosh Yaligar , Natalie Kolba ,
4
1
3
3
3,#
Vineet Tummala , Puja B. Parikh , Aurora D. Pryor , Henry J. Tannous , A. Laurie Shroyer , Thomas
Bilfinger 3,#
1
Renaissance School of Medicine, Undergraduate Medical Education, Stony Brook University, Stony Brook, NY 11794, USA.
2
Renaissance School of Medicine, Office of Dean, Stony Brook University, Stony Brook, NY 11794, USA.
3
Department of Surgery, Stony Brook University Hospital, Stony Brook, NY 11794-8191, USA.
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Department of Medicine, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
#
Authors contributed equally.
Correspondence to: Prof. A. Laurie Shroyer, Department of Surgery, Stony Brook University Hospital, Medical and Research
Translation (MART) building, 08-0814, 100 Nicolls Road, Stony Brook, NY 11794-8191, USA. E-mail:
AnnieLaurie.Shroyer@stonybrookmedicine.edu
How to cite this article: Novotny S, Dokko J, Zhang X, Agha S, Yaligar A, Kolba N, Tummala V, Parikh PB, Pryor AD, Tannous HJ,
Shroyer AL, Bilfinger T. Preoperative atrial fibrillation/flutter impact on risk-adjusted repeat aortic intervention patients. Vessel
Plus 2022;6:51. https://dx.doi.org/10.20517/2574-1209.2021.139
Received: 18 Nov 2021 First Decision: 26 Jan 2022 Revised: 2 Feb 2022 Accepted: 1 Mar 2022 Published: 2 Sep 2022
Academic Editor: Frank W. Sellke Copy Editor: Peng-Juan Wen Production Editor: Peng-Juan Wen
Abstract
Aim: Impacts of pre-operative atrial fibrillation or flutter (AF/AFL) upon repeat aortic valve replacement (r-AVR)
patients’ risk-adjusted short-term outcomes is unknown.
Methods: From 2005-2018, New York State AF/AFL versus non-AF/AFL adults’ risk-adjusted r-AVR outcomes
were compared. Primary endpoints included the Society of Thoracic Surgeons’ 30-day operative mortality or major
morbidity (MM) composite and 30-day readmission (READMIT); the MM sub-components were secondary
endpoints. Multivariable logistic regression models evaluated AF/AFL impact upon these endpoints while holding
other factors constant.
Results: Of 36,783 adults initially undergoing aortic valve replacement, 334 subsequently underwent r-AVR.
Within this r-AVR group, 42.4% of repeat surgical (r-SAVR) patients had AF/AFL; 50.4% of repeat transcatheter
(viv-TAVR) patients had AF/AFL. R-SAVR AF/AFL patients were older and had more comorbidities than those
without AF/AFL. Viv-TAVR AF/AFL patients were similar to those without AF/AFL except for lower rates of
chronic obstructive pulmonary disease. Comparing risk-adjusted r-AVR outcomes, AF/AFL did not impact MM
© The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0
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adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as
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