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Novotny et al. Vessel Plus 2022;6:51                                       Vessel Plus
               DOI: 10.20517/2574-1209.2021.139



               Original Article                                                              Open Access



               Preoperative atrial fibrillation/flutter impact on risk-

               adjusted repeat aortic intervention patients


                                           1
                                                         2
                                                                      3
                                                                                      3
                                                                                                   1
                               1
               Samantha Novotny , Julia Dokko , Xiaoyue Zhang , Sohaib Agha , Ashutosh Yaligar , Natalie Kolba ,
                                           4
                             1
                                                          3
                                                                          3
                                                                                           3,#
               Vineet Tummala , Puja B. Parikh , Aurora D. Pryor , Henry J. Tannous , A. Laurie Shroyer , Thomas
               Bilfinger 3,#
               1
                Renaissance School of Medicine, Undergraduate Medical Education, Stony Brook University, Stony Brook, NY 11794, USA.
               2
                Renaissance School of Medicine, Office of Dean, Stony Brook University, Stony Brook, NY 11794, USA.
               3
                Department of Surgery, Stony Brook University Hospital, Stony Brook, NY 11794-8191, USA.
               4
                Department of Medicine, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
               #
                Authors contributed equally.
               Correspondence to: Prof. A. Laurie Shroyer, Department of Surgery, Stony Brook University Hospital, Medical and Research
               Translation (MART) building, 08-0814, 100 Nicolls Road, Stony Brook, NY 11794-8191, USA. E-mail:
               AnnieLaurie.Shroyer@stonybrookmedicine.edu
               How to cite this article: Novotny S, Dokko J, Zhang X, Agha S, Yaligar A, Kolba N, Tummala V, Parikh PB, Pryor AD, Tannous HJ,
               Shroyer AL, Bilfinger T. Preoperative atrial fibrillation/flutter impact on risk-adjusted repeat aortic intervention patients. Vessel
               Plus 2022;6:51. https://dx.doi.org/10.20517/2574-1209.2021.139
               Received: 18 Nov 2021   First Decision: 26 Jan 2022 Revised: 2 Feb 2022  Accepted: 1 Mar 2022  Published: 2 Sep 2022
               Academic Editor: Frank W. Sellke   Copy Editor: Peng-Juan Wen  Production Editor: Peng-Juan Wen
               Abstract
               Aim: Impacts of pre-operative atrial fibrillation or flutter (AF/AFL) upon repeat aortic valve replacement (r-AVR)
               patients’ risk-adjusted short-term outcomes is unknown.
               Methods: From 2005-2018, New York State AF/AFL versus non-AF/AFL adults’ risk-adjusted r-AVR outcomes
               were compared. Primary endpoints included the Society of Thoracic Surgeons’ 30-day operative mortality or major
               morbidity (MM) composite and 30-day readmission (READMIT); the MM sub-components were secondary
               endpoints. Multivariable logistic regression models evaluated AF/AFL impact upon these endpoints while holding
               other factors constant.
               Results: Of 36,783 adults initially undergoing aortic valve replacement, 334 subsequently underwent r-AVR.
               Within this r-AVR group, 42.4% of repeat surgical (r-SAVR) patients had AF/AFL; 50.4% of repeat transcatheter
               (viv-TAVR) patients had AF/AFL. R-SAVR AF/AFL patients were older and had more comorbidities than those
               without AF/AFL. Viv-TAVR AF/AFL patients were similar to those without AF/AFL except for lower rates of
               chronic obstructive pulmonary disease. Comparing risk-adjusted r-AVR outcomes, AF/AFL did not impact MM





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