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Calafiore et al. Vessel Plus 2023;7:18  https://dx.doi.org/10.20517/2574-1209.2023.42                                       Page 7 of 21

               Table 1. Arterial inflow in arch surgery
                                                       Clinical
                           Type of cannulation                        Advantages                Disadvantages
                                                       presentation
                Antegrade flow
                  Before the AV
                           Transatrial cannulation of the LV [130,131]  A  Easy and immediate approach  Cannot be performed in case of pericardial rupture
                                                                                                the aorta cannot cross-clamped
                           Transventricular cannulation of the   A    Easy and immediate approach  Cannot be performed in case of pericardial rupture;
                              [132,133]
                           AAA                                                                  the aorta cannot be cross-clamped;
                                                                                                Cannulation of the true lumen can be difficult
                  After the AV
                                      [134]
                           AAA cannulation             A,C            Easy and immediate approach  In AAD:
                                                                                                Needs Seldinger technique with echocardiographic guidance;
                                                                                                Difficulty is the dissection is circumferential
                           Direct true lumen cannulation   A          Impossible to cannulate the false lumen  Needs to put snares around the dissected distal AA; possible rupture of the
                                       [135]
                           “samurai” technique                                                  dissected aorta;
                                                                                                Needs a (short) period of severe hypotension;
                                                                                                Possible bleeding around the snares
                           Epiaortic cannulation through the
                           (A) Axillary artery         A, C           Unfrequently dissected    Time-consuming;
                                                                                                Often needs graft interposition;
                                                                                                Size can be inadequate and wall can be fragile;
                                                                                                Possible brachial plexus injury
                           (B) Innominate artery       A, C           Easy and immediate approach  Can be dissected or atherosclerotic
                           (C) Carotid artery          A              Easy approach if common CA is used   Possible atherosclerosis;
                                                                                                Cerebral hyperperfusion?
                                                                                                Can need a separate incision
                Retrograde flow
                           Femoral artery              A, C           Easy and quick access     Can cause malperfusion or extend the dissection;
                                                                                                Can provoke atherosclerotic emboli;
                                                                                                Can be atherosclerotic and severely diseased

               AV: Aortic valve; LV: left ventricle; A: acute; SAM: systolic anterior motion; MR: mitral regurgitation; AAA: ascending aorta aneurysm; C: chronic; AAD: ascending aorta dissection; CA: carotid artery.


               hypothermia and ACP (UCP, isolated or with left common carotid artery (LCCA) perfusion), the use of axillary cannulation, if compared with other
               cannulation sites, was able to reduce marginally the prevalence of focal NDs (2.6% vs. 8.6%, P = 0.046), but substantially the prevalence of temporary NDs
                                    [35]
               (1.7% vs. 10.3, P = 0.006) .
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