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Page 6 of 11         Perezgrovas-Olaria et al. Vessel Plus 2023;7:10  https://dx.doi.org/10.20517/2574-1209.2022.54

               Table 3. Postoperative outcomes
                                                Overall          bCVG           mCVG
                Variable                                                                      P -value
                                                (n  = 1,210)     (n  = 798)     (n  = 412)
                In-hospital events
                Operative mortality             8 (0.7)          3 (0.4)        5 (1.2)       0.18
                             a
                Major adverse events            75 (6.2)         48 (6.0)       27 (6.6)      0.81
                Myocardial infarction           3 (0.2)          2 (0.3)        1 (0.2)       1
                Cerebrovascular accident        8 (0.7)          6 (0.8)        2 (0.5)       0.87
                Dialysis                        9 (0.7)          7 (0.9)        2 (0.5)       0.69
                Tracheostomy                    8 (0.7)          5 (0.6)        3 (0.7)       1
                Re-exploration for bleeding     49 (4.0)         32 (4.0)       17 (4.1)      1
                Follow-up events
                Mortality                       143 (11.8)       75 (9.4)       68 (16.5)     < 0.001
                Reoperation                     49 (4.0)         47 (5.9)       2 (0.5)       0.02 b
                                       a
               Variables are presented as count (%).  Major adverse events include operative mortality, myocardial infarction, cerebrovascular accident, dialysis,
                                              b
               tracheostomy, and re-exploration for bleeding.  P-value was calculated using the Fine and Grey method (competing risk). bCVG: Biological
               composite valve graft; mCVG: mechanical composite valve graft.








































                Figure 1. Competing risk analysis for follow-up mortality and reoperation. bCVG: Biological composite valve graft; mCVG: mechanical
                composite valve graft.

               Follow-up outcomes
               Kaplan Meier estimates showed higher follow-up mortality in the mCVG group (25.3% vs. 16.4%, P = 0.023;
               Figure 1) at 10 years. Ten-year reoperation was higher in the bCVG group (7.4% vs. 1.1%, P < 0.001;
               Figure 1).
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