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Perezgrovas-Olaria et al. Vessel Plus 2023;7:10 Vessel Plus
DOI: 10.20517/2574-1209.2022.54

Original Article Open Access

Mortality and reoperation rate of biological versus

mechanical Bentall-De Bono operation: a
propensity-matched study

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Roberto Perezgrovas-Olaria , Giovanni Jr Soletti , Mohamed Rahouma, Arnaldo Dimagli, Lamia Harik,
Gianmarco Cancelli, Mohammad Yaghmour, Hillary Polk, Brian Closkey, Jessica Wright, Mario Gaudino,
Leonard N. Girardi, Christopher Lau
Department of Cardiothoracic Surgery, Weill Cornell Medicine, New York, NY 10065, USA.
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Authors contributed equally.
Correspondence to: Dr. Christopher Lau, Department of Cardiothoracic Surgery, Weill Cornell Medicine, 525 E 68th Street, New
York, NY 10065, USA. E-mail: chl9077@med.cornell.edu

How to cite this article: Perezgrovas-Olaria R, Soletti G Jr, Rahouma M, Dimagli A, Harik L, Cancelli G, Yaghmour M, Polk H,
Closkey B, Wright J, Gaudino M, Girardi LN, Lau C. Mortality and reoperation rate of biological versus mechanical Bentall-De
Bono operation: a propensity-matched study. Vessel Plus 2023;7:10. https://dx.doi.org/10.20517/2574-1209.2022.54
Received: 6 Aug 2022 First Decision: 7 Feb 2023 Revised: 17 Mar 2023 Accepted: 25 Apr 2023 Published: 5 May 2023

Academic Editor: Carlos A. Mestres Copy Editor: Fangling Lan Production Editor: Fangling Lan

Abstract
Objective: To assess follow-up mortality and reoperation rate in patients undergoing Bentall-De Bono operation
according to the type of composite valve graft used.

Methods: All consecutive adult patients operated on between May 1997 and December 2019 at our institution
were included in the analysis and classified according to the use of a biological or a mechanical composite valve
graft (bCVG or mCVG). The primary outcomes were follow-up mortality and reoperation rate. Secondary
outcomes were operative mortality and major adverse events (MAEs) including operative mortality, myocardial
infarction, cerebrovascular accident, dialysis, tracheostomy, and re-exploration for bleeding. Kaplan-Meier and
competing risk analyses were used. Propensity matching analysis was used to balance differences in baseline
characteristics between procedures.

Results: Of 1,210 included patients, 798 received a bCVG and 412 a mCVG. The mean follow-up was 6.64 ± 0.21
years. The ten-year mortality rate was higher in the mCVG group (25.3% vs. 16.4%, P = 0.023). The ten-year
reoperation rate was higher in the bCVG group (7.4% vs. 1.1%, P < 0.001). Overall operative mortality was 0.7%,
and MAEs occurred in 6.2% of patients, with no significant differences between groups. Older age (hazard ratio

© The Author(s) 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0
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