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Page 10 of 34                             Xi et al. Soft Sci 2023;3:26  https://dx.doi.org/10.20517/ss.2023.13

               Degradable materials
               Degradable materials refer to materials that can be decomposed into simpler components over time through
               biodegradation or other chemical or physical processes . Degradable materials have many potential
                                                                 [98]
               advantages, such as reducing waste and reducing environmental impact . Over time, degradable materials
                                                                            [99]
               can be decomposed into simpler components, thus reducing the impact on the environment. In some
                                                                                           [100]
               applications, degradable materials are safer and healthier than non-degradable materials . For wearable
               sensors, some sensors need to come into direct contact with the human body, so biosafety is highly valued.
               Fortunately, most biodegradable materials have good biological safety characteristics due to their inherent
               properties. Non-degradable materials, such as plastics, can last in the environment for hundreds of years,
               causing problems such as garbage, pollution, and wildlife damage. Many degradable materials made from
               renewable resources, such as plant starch or cellulose, can be grown and harvested on a sustainable basis .
                                                                                                       [101]
               This reduces the dependence on non-renewable resources used to produce many non-degradable materials,
               such as fossil fuels. The use of degradable materials can promote the innovation of product design and
               development, thus producing more sustainable and environmentally friendly new products and
                         [102]
               applications . Bio-based  plastics,  such  as  starch-based  plastics,  polylactic  acid  (PLA),  and
               polyhydroxyalkanoate (PHA), have good plasticity and processability and can be made into products of
                                                                                                  etc.
               various shapes, sizes,       Cellulose and its derivatives, such as cellulose acetate, cellulose nitrate,      , have
                                  etc.
               good mechanical strength and heat resistance and can be used to make various materials and products.
                                                                                            etc.
               Natural  polymer  materials,  such  as  starch,  chitosan  (chitosan),  gelatin,  protein,       ,  have  good
               biocompatibility and bioactivity and can be used in various applications in the medical field. As shown in
               Figure 3C, Lan et al. reported a new type of advanced flexible ultra-soft elastic transparent material, which
               provided a unique combination of scalability, extensibility, and enzymatic degradation . Molecular
                                                                                              [101]
               weight, mechanical strength, and degradation rate can be easily adjusted. Based on these characteristics, a
               self-powered touch sensor for touch sensing and non-contact proximity detection was manufactured. These
               properties made the flexible electronic equipment degradable, making them more eco-friendly and
               environmentally friendly. As shown in Figure 3D, Chen et al. prepared magnetic bacterial cellulose of
               CoFe O  and used it to prepare a new type of flexible, biodegradable, and self-powered electromagnetic
                      4
                    2
               sensor . Magnetic CoFe O  nanoparticles were synthesized in the network structure of degradable
                     [103]
                                        4
                                      2
               bacterial cellulose, which can be completely degraded after 56 hours for flexible composite magnetic films.
               The sensor had good sensing characteristics and stability. After being installed on the monitoring smart
               sheath, it can monitor the motion signal and identify the motion state. As presented in Figure 3E, Gong
               et al. developed a highly transparent, biocompatible, fully biodegradable, and flexible TENG for energy
                                          [99]
               collection and wireless sensing . They added glycerol and polyurethane to regenerate silk fibroin, which
               greatly improved the mechanical flexibility of the silk fibroin membrane, constructed hollow silver
               nanofibers on the silk membrane to form a breathable, stretchable, biocompatible, and degradable thin
               layer,  and  was  used  as  triboelectric  electrodes.  The  sensor  obtained  can  be  used  for  touch/pressure
               sensing artificial electronic skin and can also be used as a switch to control the IoT wirelessly.

               Biodegradable green electronic materials are materials designed to naturally degrade in the environment,
               which can reduce electronic waste and pollution. These materials are typically made of biodegradable
               polymers, such as cellulose, chitosan, or PLA, which come from renewable resources and have a minimal
               environmental impact . The combination of biodegradable green electronic materials and self-powered
                                  [104]
               sensor technology can generate widely applicable biodegradable self-powered sensors, such as monitoring
               the health status of patients. There are several methods for manufacturing biodegradable self-powered
               sensors. One method is to use materials such as cellulose or PLA as substrates for sensors and then combine
               them with piezoelectric or thermoelectric power generation technology to generate energy. Another method
               is to use biomaterials such as enzymes or deoxyribonucleic acid (DNA) as sensing elements and then
               combine them with biodegradable materials to create fully biodegradable sensors.
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