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Fang et al. Plast Aesthet Res 2016;3:378-83 Plastic and
DOI: 10.20517/2347-9264.2016.06
Aesthetic Research

www.parjournal.net
Original Article Open Access

Preliminary evidence using negative

pressure wound therapy to achieve limb

salvage for the ischemic diabetic foot

Joe Chi-Cheng Fang , Yu-Tsung Chen , Yin-Shuo Chang , Jen-Hsiang Shen , Min-Ling Chen , Chang-Cheng Chang 7,8
6
2,3
1
5
4
1 School of Medicine, University of Queensland, Queensland 4072, Australia.
2 Department of Dermatology, Shuang Ho Hospital, Taipei Medical University, Taipei 235, Taipei, China.
3 School of Public Health, College of Public Health and Nutrition, Taipei Medical University, Taipei 110, Taipei, China.
4 Department of Dermatology, Taipei Medical University Hospital, Taipei 110, Taipei, China.
5 Department of Ophthalmology, Linkou Chang Gung Memorial Hospital, Taoyuan 333, Taipei, China.
6 Aesthetic Medicine Center, Department of Plastic Surgery, Chiayi Chang Gung Memorial Hospital, Puzi City, Chiayi 613, Taipei, China.
7 Department of Plastic Surgery, Chiayi Chang Gung Memorial Hospital, Puzi City, Chiayi 613, Taipei, China.
8 School of Medicine, China Medical University, Taichung 404, Taipei, China.
Correspondence to: Prof. Chang-Cheng Chang, Department of Plastic Surgery, Chiayi Chang Gung Memorial Hospital, Puzi City, Chiayi 613,
Taipei, China. E-mail: changcc1975@gmail.com
How to cite this article: Fang JCC, Chen YT, Chang YS, Shen JH, Chen ML, Chang CC. Preliminary evidence using negative pressure wound
therapy to achieve limb salvage for the ischemic diabetic foot. Plast Aesthet Res 2016;3:378-83.

Dr. Chang-Cheng Chang is a well-known microvascular reconstructive and aesthetic plastic surgeon. He is the
founder of both Wound Care Center and Aesthetic Medical Center in Chang Gung Memorial Hospital, Chia Yi, in
2010. Dr. Chang had focused his studies on wound care and aesthetic laser medicine, and had published several
papers which has proven to help increase treatment outcome in the past five years. He also works closely with the
Wound Care Center team which further comprises of plastic surgeons, cardiovascular and metabolic physicians,
rehabilitation specialists, social workers, nursing specialists and coordinators. Until present, he has published 22
peer-review scientific articles and authored one book chapter. Dr. Chang has also given numerous lectures at
various international societies and centers and received national honorable awards. He is now serving as the head
in Aesthetic Medical Center, China Medical University Hospital, Taichung, Taipei, China.

ABSTRACT
Article history: Aim: Negative pressure wound therapy (NPWT) in diabetic foot ulcers (DFU) has been
Received: 22-02-2016 discussed in several studies, but without a focus on peripheral arterial disease (PAD), which is
Accepted: 09-08-2016 a common comorbidity. This study aims to investigate the feasibility of NPWT in the treatment
Published: 20-12-2016 of DFU with PAD in regards to limb salvage and the clinical course. Methods: The authors
retrospectively collected patients with DFU and PAD diagnosed with either Doppler ultrasound
Key words: or angiography as the PAD study group. Patients with DFU but no PAD were enrolled as the
Negative pressure wound therapy, non-PAD comparison group. NPWT was applied to both PAD and non-PAD subjects. Results:
diabetic foot ulcer, There were 10 patients in the PAD group and 3 patients in the non-PAD group. In the PAD

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