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Figure 1: The costs incurred for each type of reconstruction when additional admissions and surgery secondary to explantation are taken into account

          tissue, LD flaps with breast implants, expanders with   immediate reconstruction were randomly assigned to either
          implant exchange and immediate implant placement. They   the Natrelle™ 150 or Becker™ Siltex implant. Aesthetic
          concluded “that autologous pedicled tissue was slightly   outcomes were evaluated by an expert panel who also
          more cost‑effective than free tissue reconstruction”, and   tried to recognize which implants the breasts were
          that “implant based techniques were not cost‑effective”.  reconstructed with. The results showed that there was no
          Damen  et al.  compared silicone implants, implants   difference between the two groups in terms of symmetry,
                      [13]
          preceded  by  tissue  expansion,  LD  flaps  and  deep  inferior   outcome scores and patient satisfaction. The expert panel
          epigastric perforator flaps in 427  patients in a single   guessed  the  right  implant  shape  in  42% of the  Natrelle™
          Dutch  center.  They  found  that  immediate  one‑stage   150 implants and 66% of the round implants.
          reconstructions have lower costs compared with flap   There have been a number of studies [15‑18]  assessing survival
          procedures and tissue expander reconstructions. To   of  the  Becker™  permanent  expanders  with  variable

          date,  there  have  been  no  cost  analysis  solely  comparing   results.  Taboada‑Suarez  et  al.  reviewed 314 Becker™
                                                                                        [19]
          one‑stage and two‑stage reconstruction.
                                                              permanent expander’s implants in 237 patients, and found
          At present, there are only two expander implants on the   “a mean survival time  to explantation of 120  months”.
          UK market designed for a one‑stage reconstruction: the   Farace  et  al.  found that  77 of Becker™  implants  were
                                                                         [20]
          Natrelle™ 150 and the Becker™ Siltex. The Natrelle™   removed within 5  years in a cohort of 99  patients.
          150  implant is used for one‑stage reconstruction at   Goh et al.  found an explantation rate of 25% at a mean
                                                                      [21]
          this  center because the  surgeon has been  trained in   follow‑up of 64.6  months.  There  is  much less  published
          its use and is most familiar with this product. There is   data on the  longevity  of the  Natrelle™ 150 implant.
          no clear benefit  of using  one expander implant over   Gui et al.  studied 107 patients with 129 reconstructions
                                                                      [22]
          the other apart from surgeon or patient preference. In   with the Natrelle™ 150 and found a low 3.9% explantation
          fact, a paper  published in  November  2010 compared   rate at a mean of 18  months.  Cicchetti  et  al.  analyzed
                                                                                                      [4]
                     [14]
          aesthetic outcome and  patient satisfaction between   97 consecutive patients who received a 107  Natrelle™
          patients  who  had  received  the  Natrelle™  150  implant  and   150  expander implants and their data show an overall
          Becker  Siltex  implant. Two groups of patients  who were   explantation rate  of 25% by  6  years.  Despite  its  primary
          all  undergoing  bilateral, prophylactic mastectomy and   design of permanent expanders being  “permanent”,

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