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either tertiary centers or local hospitals with appropriate
                 1.0                                          consulting. Presumably, the delay between detecting the
                                                              lump and getting treatment was short because upper limb
                 0.8                                          tumors are easily found by the patients themselves, and
                                                              even small tumors are visible in this area. However, this
                 0.6                                          study showed that even though the tumors were biopsied
                                                              incisionally, this did not result in cancer spreading or poor
                                                              survival. The patients whose tumors were incisionally
                 0.4                                          biopsied had the same outcomes with those whose
                                                              tumors were diagnosed according to the national practice
                 0.2                                          guidelines. According to the literature, the risk of residual
                       TIME_PERIOD=A                          tumor tissue is 24–60% after an unplanned surgery [10,11]
                 0.0   TIME_PERIOD=B                          and therefore confirms the fact that unplanned surgery
                                                                                                   But still many
                                                              increases the risk of local recurrence.
                                                                                               [12,13]
                   0  200 400 600 800 1,000 1,200 1,400
                                                              patients are operated in tertiary centers without accurate
          Figure 1: Soft-tissue sarcoma specific survival between the time periods;   imagining and biopsy. [14,15]
          Group A (green) and Group B (red)
                                                              There were many patients who had had a previous benign
          after the knowledge about tumor diagnostics improved.   tumor in the same location. In addition to the previous
          In the latter years of the study, the number of sarcoma   tumor diagnosis and treatment, the newly formed tumor
          patients increased. In the year 2001 there were 8 patients   should always be examined as an independent disease,
          diagnosed with STS, in 2008; 19 patients and in 2009;   according to the recommendations. Furthermore, we
          15 patients. This likely resulted from improved knowledge   found that in some cases histological evaluation was
          of these tumors by primary care practitioners and   never made and thus the diagnosis was delayed.
          improved referral patterns to specialized units.    National guidelines are still not being followed correctly.

          When comparing our single institution’s STS results   Sarcomas are being incisionally biopsied without
          with a nationwide population based study in Finland, no   appropriate imagining. A failure to implement guidelines
          statistically significant differences in surgical treatment,   is primarily due to the rarity of this malignancy. Only a
                                                      [5]
          local recurrence, metastasis or survival were noted.  STS   few doctors come to face STS during their practice and
          local recurrence in our series was 22% and as opposed to   therefore the guidelines are not easy to remember. To
          30% in earlier studies. [1]                         increase the awareness of tumor diagnostics, the national
                                                              guidelines should be effectively and repeatedly processed
          In this study, Group B had more metastases [Figure 1]   in tertiary centers. Written recommendations in the
          a lower survival rate as well as a shorter survival time.   Internet are not enough. Guidelines have to be introduced
          We also noted that the 1st year survival was better in   by personal education, lectures, and program with easy
          Group A. Because this was a retrospective study, we   availability to all doctors who take part in referring
          were not able to analyze the effect histologic grading   patients to specialized units.
          on cervical. Between the years, 2000 and 2009 sarcomas
          were primarily divided into 3 histologic grades: grade I   REFERENCES
          presenting the low-grade tumors and Grade II and III the
          high-grade tumors. This histological grading system is   1.   Cutts S, Andrea F, Piana R, Haywood R. The management of soft tissue
          proposed by the French Federation of Cancer Centers and   sarcomas. Surgeon 2012;10:25-32.
          is the most commonly used system for assigning tumor   2.   Gronchi A, Lo Vullo S, Colombo C, Collini P, Stacchiotti S, Mariani L, Fiore M,
          grading. [6,7]  Although there were only minimal differences   Casali PG. Extremity soft tissue sarcoma in a series of patients treated at a single
          in grading between the groups, it is notable that Grade   3.   institution: local control directly impacts survival. Ann Surg 2010;251:506-11.
                                                                  King DM, Hackbarth DA, Kirkpatrick A. Extremity soft tissue sarcoma
          III tumors were equally prevalent in the 2 groups       resections: how wide do you need to be? Clin Orthop Relat Res 2012;470:692-9.
          studied: (A: 43%, B: 45%).                          4.   Khatri VP, Goodnight JE Jr. Extremity soft tissue sarcoma: controversial
                                                                  management issues. Surg Oncol 2005;14:1-9.
          Despite the grading, we found that tumors in the    5.    Popov P, Tukiainen E, Asko-Seljavaara S, Huuhtanen R, Virolainen M,
          Group B to be more likely to have metastases with a     Virkkunen P, Blomqvist C. Soft-tissue sarcomas of the upper extremity:
          lower overall survival rate. After consideration of all   surgical treatment and outcome. Plast Reconstr Surg 2004;113:222-30.
          parameters studied, we found that there were more trunk   6.   Nystrom LM, Reimer NB, Reith JD, Dang L, Zlotecki RA, Scarborough MT,
                                                                  Gibbs CP Jr. Multidisciplinary management of soft tissue sarcoma. Scientifi c
          sarcomas in the Group B. Many studies have shown        World Journal 2013;2013:852462.
          that sarcomas located in the trunk (chest wall, internal   7.   Trojani M, Contesso G, Coindre JM, Rouesse J, Bui NB, de Mascarel A,
          trunk and retroperitoneum) have a worse prognosis and a   Goussot JF, David M, Bonichon F, Lagarde C. Soft-tissue sarcomas of adults;
          higher rate for local recurrence. [1,8,9]  This is mainly due to   study of pathological prognostic variables and defi nition of a histopathological
                                                                  grading system. Int J Cancer 1984;33:37-42.
          the difficulty of gaining adequate resection margins and   8.   Gutierrez JC, Perez EA, Franceschi D, Moffat FL Jr, Livingstone AS,
          lack of thick barriers such as the muscle fascia’s.     Koniaris LG. Outcomes for soft-tissue sarcoma in 8249 cases from a large
                                                                  state cancer registry. J Surg Res 2007;141:105-14.
          Interestingly, a remarkable number of upper limb tumors   9.   Sugiura H, Nishida Y, Nakashima H, Yamada Y, Tsukushi S, Yamada K.
          were diagnosed by an incisional biopsy. This was done in   Surgical procedures and prognostic factors for local recurrence of soft tissue

          Plast Aesthet Res || Vol 1 || Issue 3 || Dec 2014                                                 101
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