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Topic: State of the Art in the Management of Oral Squamous Cell Carcinoma





            Elective neck dissection in oral squamous

            cell carcinoma of the upper maxilla:

            necessary?





            Manuel Moreno-Sánchez

            Department of Oral and Maxillofacial-Head and Neck Surgery, University Hospital Infanta Cristina, 06080 Badajoz, Spain.
            Correspondence Author: Dr. Manuel Moreno-Sánchez, Department of Oral and Maxillofacial-Head and Neck Surgery, University
            Hospital Infanta Cristina, Avenida de Elvas s/n, 06080 Badajoz, Spain. E-mail: manumorenosanchez@hotmail.com

                              Dr. Manuel Moreno-Sánchez, M.D., obtained his Medical Degree at the University of Extremadura
                              School of Medicine in Badajoz, Spain, in 2010. After that, he began to work as Resident Surgeon of
                              Oral and Maxillofacial Surgery at the University Hospital Infanta Cristina, Badajoz, Spain. He is also
                              University Honorary Collaborator at the University of Extremadura and he has completed a Master’s
                              Degree in Biomedicine. Currently, he is a postgraduate student at the Program of Modeling and
                              Experimentation in Science and Technology of the University of Extremadura.




                  ABSTRACT
                  Aim: Surgical treatment of clinically negative neck in maxillary squamous cell carcinoma (SCC) of
                  the upper jaw is controversial. The purpose of this systematic review was to define the incidence
                  of cervical metastasis and to assess if elective neck dissection is justified when the neck is not
                  primarily affected. Methods: An electronic literature search was conducted in several databases,
                  including MEDLINE, EMBASE, and Cochrane Central databases, for articles written in English.
                  Results: Twenty-eight articles were included in the review. The overall cervical metastases rate
                  was 33% and the total initial cervical metastases rate was 16%. Interestingly, the author found
                  that 71% of patients with cervical metastases from maxillary SCC carcinoma were T3/T4 stage.
                  Conclusion: This review shows the need for a change in the management of the N0 neck in SCC
                  arising in the maxillary alveolus and hard palate. Elective neck dissection should be performed in
                  patients with T3/T4 tumours with clinic or radiographic negative necks (N0c).
                  Key words:
                  Elective neck dissection; maxilla squamous cell carcinoma; surgical treatment; cervical lymph
                  node metastasis



            INTRODUCTION                                      frequent than SCC from other oral sites such as tongue,
                                                              floor of mouth or retromolar region. Many studies [1-5]
            Squamous cell carcinoma (SCC) located in the maxillary
            gingiva and hard palate is relatively rare and less   This is an open access article distributed under the terms of the Creative
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                                                               How to cite this article:  Moreno-Sánchez M. Elective neck
                                                               dissection in oral squamous cell carcinoma of the upper maxilla:
                                    DOI:                       necessary? Plast Aesthet Res 2016;3:175-80.
                                    10.20517/2347-9264.2016.18
                                                               Received: 02-04-2016; Accepted: 02-06-2016
             © 2016 Plastic and Aesthetic Research | Published by OAE Publishing Inc.                      175
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