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Page 2 of 11           Gimenez et al. Plast Aesthet Res 2022;9:28  https://dx.doi.org/10.20517/2347-9264.2021.129

               reconstructive plan. Furthermore, the wide variety of etiologies responsible for producing the defect in
               question informs the reconstructive approach in distinctive ways. Compared to adults, restoring form and
               function in children often poses increased technical challenges and necessitates the reconstructive surgeon
               account for future growth. In this article, we discuss the evaluation and management of soft tissue defects of
               the leg in the pediatric population as well as important considerations inherent to this patient demographic.


               MULTIDISCIPLINARY APPROACH TO CARE
               The management of patients with extensive lower extremity defects is highly complex as patients often
               require multiple surgical procedures, have prolonged hospitalizations, and frequently experience profound
               psychosocial impairment. As is true with other forms of reconstructive surgery, multidisciplinary
               collaboration between the reconstructive surgeon and other surgical and non-surgical specialists is essential
               to optimize outcomes . Of multidisciplinary collaborations, none have had as transformative an impact on
                                 [1-4]
               patient outcomes as the orthoplastic approach. The orthoplastic approach to lower extremity reconstruction
               entails extensive collaboration between orthopedic and plastic surgeons when evaluating lower extremity
                                                 [5,6]
               defects and developing the surgical plan . Using this approach, the orthopedic surgeons typically perform
               skeletal reconstruction whilst the plastic surgeons reconstruct the overlying soft tissue; however, the plastic
               surgery team may become involved in skeletal reconstruction should free transfer of vascularized bone to be
               incorporated into the reconstructive plan. Over time, this approach has evolved to include the expertise of
               vascular surgeons, radiologists, infectious disease and pain management doctors, and physical therapists .
                                                                                                        [6]
               Several studies have validated the utility of this multidisciplinary approach in the trauma setting, noting
               shorter time to bony healing, increased rates of free tissue transfer when indicated, decreased rates of bony
               and soft tissue infections, and healing by secondary intention . Additionally, similar beneficial effects have
                                                                  [7-9]
               been observed in patients with chronic wounds and oncologic defects managed by a multidisciplinary care
               team comprised of both orthopedic and plastic surgeons [10,11] .


               In addition to optimizing reconstructive outcomes, it is important to address the psychological impact that
               significant insults to the lower extremity can have on children and adolescents. Pediatric patients, in
               particular, are highly susceptible to developing acute stress disorder and post-traumatic stress disorder
               secondary to both the cause of lower extremity injury and its associated management [12-15] . As such, the
               inclusion of psychologists and psychiatrists in the multidisciplinary care team and mindful postoperative
               management is paramount to minimizing psychological morbidity.


               PREOPERATIVE CONSIDERATIONS
               Successful lower extremity reconstruction is dependent on meticulous preoperative planning based on a
               comprehensive  history  and  physical  examination.  When  performing  the  initial  assessment,  the
               reconstructive surgeon must identify risk factors that may preclude the use of some surgical options or
               complicate wound healing following surgery. Children requiring lower extremity reconstruction typically
               have fewer comorbidities than adults; however, it is prudent to assess for obesity, diabetes, congenital
               pulmonary or cardiovascular diseases, coagulopathies, and malnutrition states. In cases of oncoplastic
               reconstruction, it is imperative to discuss any neoadjuvant and adjuvant chemoradiation plans
               preoperatively as this will inform the timeline and type of reconstruction performed [16,17] .


               When evaluating the lower extremity defect, the orthoplastic care team must determine its size, depth,
               location along the leg, along with the viability and laxity of surrounding tissue. Additionally, exposed,
               damaged, and missing vital tissues including bone, neurovascular structures, and tendons, should also be
               noted on examination. In trauma patients, aggressive debridement of non-viable tissue is needed to fully
               ascertain the defect’s size and extent and decrease the risk of infection following surgery [18,19] . Additionally,
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