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Case Report

Angioplasty and stenting for a young stroke

patient diagnosed as cerebrovascular

fibromuscular dysplasia

Jia‑Ping Xu, Yong‑Jun Cao, Guo‑Dong Xiao, Chun‑Yuan Zhang, Ji‑Jun Shi
Department of Neurology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, Jiangsu, China.

ABSTRA CT

Fibromuscular dysplasia (FMD) is a noninflammatory, nonatherosclerotic, and multifocal vascular disease, commonly involving the
cerebral and renal arteries. Cerebrovascular stenosis and spontaneous dissection resulting from cerebrovascular FMD (cFMD) is
one of the important causes of young stroke. Here, we reported the case of cFMD in a 28‑year‑old male patient with stroke. Digital
subtraction angiogram demonstrated a dissecting aneurysm in the carotid artery and multiple stenoses in both vertebral arteries.
Endovascular angioplasty with balloon predilation and stenting was successfully performed for the patient when the medical treatment
was not adequate. The follow‑up showed a remarkable improvement and no recurrence of stroke.

Key words: Angioplasty, fibromuscular dysplasia, stent, therapy, young stroke

INTRODUCTION Affiliated Hospital of Soochow University because
of ischemic stroke with inarticulate speech and
Fibromuscular dysplasia (FMD) is an uncommon paralysis of right limbs. The patient had no medical
vascular disease that occurs more often in young women. history of traditional cerebrovascular risk factors,
FMD mainly involves the renal and cerebral arteries. like hypertension. The patient also had no personal
[1]
Cerebrovascular FMD (cFMD) can be complicated by or family history of stroke. The dysphasia and slight
stroke and associated with headaches, and it can also right‑sided weakness occurred without the definite
be associated with intracranial aneurysms with a high causes for 1‑day before the admission without any prior
risk of subarachnoid hemorrhage. The cerebrovascular warning. Magnetic resonance imaging revealed a new
stenosis and dissection, as a result of FMD, is one of the infarction lesion on the left temporal lobe and occlusion
important causes of stroke in the young (15‑45‑year‑old). of the left internal carotid artery (ICA). The ultrasound
A case report of cFMD treated with angioplasty and sonography also demonstrated the occlusion in the
stenting in a young male patient is presented, along left ICA. Antiplatelet (clopidogrel 75 mg and aspirin
with an overview of the available literature. 100 mg q.d. p.o.), and statin therapy (atorvastatin
40 mg q.n. p.o.) were given to this patient, diagnosed
CASE REPORT as acute cerebral infarction without a clear etiology.
During this hospitalization for 7 days, logaphasia, and
A 28‑year‑old male patient was admitted to our stroke more severe paralysis of the right limbs occurred. Then,
unit ward of Department of Neurology in the Second he was transferred to our stroke unit ward for further
vascular evaluation and interventional therapy. The
Corresponding Author: Dr. Ji‑Jun Shi, positive neurological signs were as follows: incomplete
Department of Neurology, The Second Affiliated logaphasia, central facial paralysis, right‑sided
Hospital of Soochow University, No. 1055, hemiparesis (4/5), and positive Babinski sign. Other
Sanxiang Road, Suzhou 215004, Jiangsu, China.
E‑mail: shijijun2008@126.com
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Cite this article as: Xu JP, Cao YJ, Xiao GD, Zhang CY, Shi JJ. Angioplasty
DOI: and stenting for a young stroke patient diagnosed as cerebrovascular
10.4103/2347-8659.167310 fibromuscular dysplasia. Neuroimmunol Neuroinflammation 2015;2:291-4.
Received: 08-06-2015; Accepted: 06-08-2015

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