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Page 10 of 19  Son et al. Microbiome Res Rep. 2025;4:29  https://dx.doi.org/10.20517/mrr.2025.14



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 Table 3. Changes in RA of jejunal mucosa-associated microbiota in nursery pigs challenged with F18  E. coli
 Inoculation   Inoculation   Days post   Response 1
 Ref.
 BW (kg)  age (d)  inoculation (d)  Phylum  Family  Genus        Species

 Duarte and   NA  28  21  No effect  Helicobacteraceae ↑ Pseudomonadaceae ↑   Helicobacter ↑   Helicobacter rappini ↑ Helicobacter
 [23]                                                                     #
 Kim  Xanthomonadaceae ↑ Peptostreptococcaceae ↑   Campylobacter ↓  equorum ↑
                                                                                           #
 Campylobacteraceae ↓ Enterobacteriaceae ↓                       Streptococcus hyointestinalis ↑
 Brachyspiraceae ↓ Caulobacteraceae ↓                            Campylobacter coli ↓ Acinetobacter
                                                                 lwoffii ↓
                                                          #
 Garavito-Duarte  6.3  28  21  Bacteroidetes ↑   Prevotellaceae ↑ Lachnospiraceae ↑   Lactobacillus ↓    Helicobacter equorum ↑
 [27]  #                   #                                #
 et al.  Spirochaetae ↑  Ruminococcaceae ↑ Lactobacillaceae ↓    Bifidobacterium ↓  Bifidobacterium dentium ↓
           #
 Bifidobacteriaceae ↓                                            Lactobacillus delbrueckii ↓
                                                                 Bifidobacterium boum ↓
                                                                 Lactobacillus salivarius ↓
 [28]
 Gormley et al.  6.4  28  21  -  -            Bradyrhizobium ↑   -
                                              Eubacterium ↑
                                              Romboutsia ↑
                                              Selenomonas ↑

                                              Terrisporobacter ↑
                                              Prevotella ↑
                                              Solobacterium ↓
                                              Bacillus ↓
                                              Corynebacterium ↓
 [9]  #      #
 Duarte et al.  6.9  28  21  Bacteroidetes ↓  Acidaminococcaceae ↓  -  Prevotella stercorea ↓
                                                                 Phascolarctobacterium
                                                                              #
                                                                 succinatutens ↓
                                                                                       #
                                                                 Lactobacillus delbrueckii ↓
                                                                               #
                                                                 Prevotella copri ↓
 [29]
 Jang et al.  7.2  28  21  No effect  No effect  -               -
 [30]        #
 Xu et al.  7.1  28  21  No effect  Campylobacteraceae ↓  Selenomonas ↓  Helicobacter rodentium ↑
 [36]      #               #                              #                    #
 Duarte et al.  8.2  28  13  Proteobacteria ↑   Helicobacteraceae ↑  Prevotellaceae ↓    Helicobacter ↑  Prevotella copri ↓
        #              #
 Bacteroidetes ↓   Veillonellaceae ↓  Clostridiaceae ↓  Mitsuokella ↓   Selenomonas bovis ↓
 Firmicutes ↓                                 Selenomonas ↓      Roseburia faecis ↓
                                              Megasphaera ↓      Selenomonas lipolytica ↓
                                                                 Acidaminococcus fermentans ↓
 [37]
 Duarte et al.  8.2  NA  21  Proteobacteria ↑  Helicobacteraceae ↑ Prevotellaceae ↓ Lactobacillaceae ↓   -  Helicobacter mastomyrinus ↑
         #                     #
 Bacteroidetes ↓  Lachnospiraceae ↓  Campylobacteraceae ↓        Prevotella copri ↓
 Firmicutes ↓                                                    Prevotella stercorea ↓ Roseburia
                                                                 faecis ↓

 1
 All results represent statistically significant changes (P < 0.05) in the positive control (E. coli-challenged group) relative to the negative control (non-challenged group), except for those marked with a hash (#),
 which indicate a statistical tendency (P < 0.10). RA: Relative abundance; E. coli: Escherichia coli; BW: body weight; NA: not available.
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