Page 18 - Read Online

Zhao et al. Microbiome Res Rep. 2025;4:28 https://dx.doi.org/10.20517/mrr.2025.12 Page 13 of 13

48. Liang C, Zhou XH, Gong PM, et al. Lactiplantibacillus plantarum H-87 prevents high-fat diet-induced obesity by regulating bile acid
metabolism in C57BL/6J mice. Food Funct. 2021;12:4315-24. DOI PubMed
49. Watanabe M, Houten SM, Wang L, et al. Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c. J
Clin Invest. 2004;113:1408-18. DOI PubMed PMC
50. Zhang H, Dong M, Liu X. Obeticholic acid ameliorates obesity and hepatic steatosis by activating brown fat. Exp Ther Med.
2021;22:991. DOI PubMed PMC
51. Münzker J, Haase N, Till A, et al. Functional changes of the gastric bypass microbiota reactivate thermogenic adipose tissue and
systemic glucose control via intestinal FXR-TGR5 crosstalk in diet-induced obesity. Microbiome. 2022;10:96. DOI PubMed PMC
52. Zhang J, Zhou J, He Z, et al. Salidroside attenuates NASH through regulating bile acid-FXR/TGR5 signaling pathway via targeting gut
microbiota. Int J Biol Macromol. 2025;307:142276. DOI PubMed
53. Sun H, Guo Y, Wang H, et al. Gut commensal Parabacteroides distasonis alleviates inflammatory arthritis. Gut. 2023;72:1664-77.
DOI PubMed
54. Gong Z, Zhou J, Zhao S, et al. Chenodeoxycholic acid activates NLRP3 inflammasome and contributes to cholestatic liver fibrosis.
Oncotarget. ;7:83951-63. DOI PubMed PMC
55. Yue H, Li Y, Cai W, Bai X, Dong P, Wang J. Antarctic krill peptide alleviates liver fibrosis via downregulating the secondary bile acid
mediated NLRP3 signaling pathway. Food Funct. 2022;13:7740-9. DOI PubMed
56. Sun X, Chen Z, Yu L, et al. Bacteroides dorei BDX-01 alleviates DSS-induced experimental colitis in mice by regulating intestinal bile
salt hydrolase activity and the FXR-NLRP3 signaling pathway. Front Pharmacol. 2023;14:1205323. DOI PubMed PMC
57. Puri P, Daita K, Joyce A, et al. The presence and severity of nonalcoholic steatohepatitis is associated with specific changes in
circulating bile acids. Hepatology. 2018;67:534-48. DOI PubMed PMC
58. Liu C, Du MX, Abuduaini R, et al. Enlightening the taxonomy darkness of human gut microbiomes with a cultured biobank.
Microbiome. 2021;9:119. DOI PubMed PMC
59. Abu-Ali GS, Mehta RS, Lloyd-Price J, et al. Metatranscriptome of human faecal microbial communities in a cohort of adult men. Nat
Microbiol. 2018;3:356-66. DOI PubMed
60. Loomba R, Seguritan V, Li W, et al. Gut microbiome-based metagenomic signature for non-invasive detection of advanced fibrosis in
human nonalcoholic fatty liver disease. Cell Metab. 2017;25:1054-62.e5. DOI PubMed PMC