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Page 10 of 15 Cossu et al. Mini-invasive Surg 2020;4:60 I http://dx.doi.org/10.20517/2574-1225.2020.52
Tumor control 100% NS 2 (100%) NS NS 10 contolled (6/6 or 100% pts with surgery + SRT) 5 progression NS 14/14 pts with no previous RT (100%) 2/6 with previous TT controlled tumor 2/6 died 3 (100%)
Mean FU 71 mo NS 18 mo 14 mo 37 mo 21 mo NS 57 mo 54 mo
RT protocol 13 SRT 2 SRS 2 PBRT 1 RT SRS 6 RT None 6 SRT NS SRT 54Gy in 30fr 11/14 None
CN palsy improvement Endocrinological improvement 16/28 (57%) 15/17 (88.2%) Or 32/34 (94%) NS NS NS 5/7 (71%) NS 4/6 (67%) 8/15 6 stable NS 2/7 8/14 (57%) 2/6 (33%) 4/6 pts with ON decompression had improvement (66%) NS
Table 2. Summary of the surgical series reporting an endoscopic management of patients with cavernous sinus meningiomas
Other complications 0 NS 1 CSF leakage 2 0 1 VP shunt and 1 meningitis (also transcranial approach performed) NS 0 NS NS 1 CSF leak 1 DVT (3.8%) 2 ICA injuries (7.1%; 1 died) 1 CSF leak and meningitis 3 0 CN: cranial nerve; CSF: cerebrospinal fluid; DVT: deep venous thrombosis; GTR: gross total resection; PBRT: proton beam radiotherapy; fr: fractions; FU: follow-up; Gy: gray; NS: not specified; ON: optic From a radiobiolog
Postop new endocrinopathies 1 0 0 NS 0 0 (1 after SRT) 2 (7.1%) 0 0 nerve; RT: radiotherapy; SRS: stereotactic radiosurgery; SRT: stereotactic radiotherapy; STR: subtotal resection; TOT: total; TT: treatments; VP: ventriculoperitoneal with selective coverage and steep radiation falloff with sparing of normal tissues are the keys to a successful treatment.
Postop new CN palsies 0 0 0 1/7 (14%) 0 1 4 (14.3%) 1 immediate 2 delayed TOT 3/8 (38%) 0
Treatment plan 17 Surgery + RT 4 only surgery Surgery +/- RT STR + SRS 8 STR 1 GTR 4 GTR 2 STR 9 surgery 6 surgery + RT 2 GTR 14 STR Surgery + SRT if no previous RT and growth at FU Only surgery 1 GTR 2 STR
No. pts (6 previous COMBINED AND ADJUVANT STRATEGIES
21 2 2 9 6 15 20 TT) 3
Akutsu et al. [30] 2009 Liu et al. [36] 2009 Graillon et al. [31] 2014 Khan et al. [33] 2014 Zhang et al. [18] 2014 Lobo [32] 2015 Koutourousiou [35] 28 2017 Sivakumar [28] 2019 Zhang [34] 2019
