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Page 4 of 19           Ackerman et al. Mini-invasive Surg 2021;5:14  https://dx.doi.org/10.20517/2574-1225.2021.02

               Anesthesia
               The patient should be anesthetized under general anesthesia with a double-lumen endotracheal tube,
               adequate IV access, and invasive hemodynamic monitoring. If a central venous catheter is inserted, we
               prefer to avoid the left neck and chest in the event a cervical esophagostomy is required. The position of the
               double lumen endotracheal tube is confirmed with fiberoptic bronchoscopy. Alternatively, newer double
               lumen endobronchial blockers may be utilized through a single lumen endotracheal tube (Rusch EZ-
               Blocker, Teleflex). All patients receive venous thromboembolism prophylaxis with sequential compression
               devices and subcutaneous heparin. Perioperative antibiosis should comply with Surgical Care Improvement
               Project measures, with cefazolin being the first-line of choice . Communication between the surgeon and
                                                                   [26]
               anesthesia provider is crucial to the conduct of the operation. The surgeon should be made aware of the
               patient’s hemodynamic changes at all times. Once the gastric vasculature is divided, hypotension should
               generally be treated with volume expansion as opposed to vasopressors to minimize conduit ischemia.

               Endoscopy
               Flexible fiberoptic esophagogastroscopy is routinely performed at our institution. This allows for a final
               assessment of the esophageal pathology for which the esophagectomy is indicated. The stomach and
               esophagus should be decompressed on withdrawal of the scope to allow for safe laparoscopic port
               placement and subsequent visualization.

               Laparoscopy
               Ivor Lewis esophagectomy begins in the abdomen and progresses through an assessment for metastatic
               disease, esophagogastric mobilization with lymphadenectomy, conduit creation, pyloroplasty, and feeding
               jejunostomy insertion.


               Positioning
               The patient is placed in a supine position on the operating table with a footboard to allow for safe steep
               reverse-Trendelenburg positioning. The left arm is tucked and the right arm is extended to approximately
               45 degrees. For non-robotic procedures, the surgeon stands on the patient’s right side with the assistant
               standing on the left. A liver retractor (Lapro-Flex® Triangular Retractor, Mediflex, Islandia, NY) is attached
               to the right side of the bed between the knee and hip.


               Port placement
               Abdominal port placement is shown in Figure 1. Although we find these locations to be the most useful,
               port placement may vary based on surgeon preference or patient factors. The peritoneal cavity is accessed
               per surgeon comfort, although we prefer starting with an optical separator 5 mm robotic port in the left
               midclavicular line approximately 3 cm inferior to the costal margin. This port will be replaced with an 8 mm
               robotic port and used for the robotic right arm (arm 3). In a potentially hostile abdomen, the location and
               method of entry should be tailored to the scenario with a focus on safety. The abdomen is insufflated, and a
               30-degree camera is introduced into the abdomen. Adhesiolysis is performed as necessary to facilitate
               placement of subsequent ports under direct laparoscopic visualization. Three additional robotic working
               ports, a port for the liver retractor, and two bedside assistant ports are placed. The additional robotic ports
               include a 12 mm robotic port with an 8 mm reducing sheath in the right midclavicular line approximately
               one-third from the umbilicus to xiphoid for the robotic left arm and stapler (arm 1), an 8 mm robotic port
               just to the left of midline approximately one-third from the umbilicus to xiphoid for the camera (arm 2),
               and an 8 mm robotic port in the left anterior axillary line 2-3 cm inferior to the costal margin for the robotic
               assist (arm 4). The laparoscopic liver retractor port is placed inferior to the costal margin in the right
               midaxillary line just anterior to the peritoneal reflection of the hepatic flexure of the colon. The bedside
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