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Ziogas et al. Mini-invasive Surg 2020;4:69  I  http://dx.doi.org/10.20517/2574-1225.2020.63                                     Page 7 of 11

               ECONOMIC COST
               Mejia et al.  reported that the adjusted room and board charges were significantly lower in the LMH vs.
                         [46]
               the RMH group, with no other difference between the two groups regarding economic cost. Of note, when
               comparing the cost of LMH vs. RMH, the fixed capital cost ($1,000,000-$2,600,000 for a robotic system
                                                                                         [120]
               with a 10-year longevity period) [117-120]  and annual maintenance cost ($90,000-$175,000)  for a hospital to
               purchase and maintain a surgical robot, should also be taken into consideration. The addition of this cost
               can be burdensome, particularly for low-volume liver surgery centers, and this remains a significant driving
               factor for the slow spread of RMH and robotic liver surgery in general. It should also be noted that access
               to the robot in the operating room can be a challenge due to competition with other surgical service lines.


               CONCLUSION
               The introduction of laparoscopy and robotic surgical systems in liver surgery has significantly changed the
               current state of practice. Although both approaches have been more widely tested for minor liver resections,
               the number of LMHs and RMHs performed worldwide has significantly increased over recent years, and
               is still on the rise. Although there is a considerable deviation in outcomes after RMH, especially during
               early experience, when RMH is performed by experienced surgeons in high-volume liver centers, it can be
               associated with equivalent operating time, EBL, LOS, morbidity and mortality, and comparable oncologic
               outcomes in terms of achieving a margin-negative resection and long-term overall survival. The fixed capital
               and annual maintenance costs for the robotic surgical system may pose a significant obstacle in the broader
               adoption of RMH, particularly in low-volume centers.



               DECLARATIONS
               Authors’ contributions
               Study concept, data acquisition, data analysis and interpretation, drafting, critical revision, final approval of
               the manuscript: Ziogas IA, Tohme S, Geller DA


               Availability of data and materials
               Not applicable.


               Financial support and sponsorship
               None.


               Conflicts of interest
               All authors declared that there are no conflicts of interest.

               Ethical approval and consent to participate
               Not applicable.

               Consent for publication
               Not applicable.

               Copyright
               © The Author(s) 2020.


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