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Page 18 of 23            George et al. Mini-invasive Surg 2024;8:4  https://dx.doi.org/10.20517/2574-1225.2023.102

               Table 8. Table of AI application in capsule endoscopy for bowel prep scoring
                              Year of   Study     Study                 Training/Validation   AI
                Ref.  Application                        Aim and goals                          Results
                              publication  design  location             dataset            type
                Nam   Bowel prep   2021  Retrospective Korea  Automatically detect   Training: 500 images for   CNN Sensitivity of
                et al. [100]  scoring                    and score bowel prep  each score (1-5), totalling   93%,
                                                         quality on CE images  2,500            specificity of
                                                                        Testing: 96 CE cases    100%
                                                                                                At cleansing
                                                                                                cut-off value of
                                                                                                3.25
               AI: Artificial intelligence; CE: capsule endoscopy; CNN: convolutional neural network.


               Table 9. Table of AI applications in capsule endoscopy for multiple lesion detection
                Ref.  Application  Year of   Study   Study   Aim and goals  Training/Validation   AI type Results
                               publication design
                                                                     dataset
                                                  location
                Park    Multiple   2020  Retrospective Korea  Develop CNN   Training: 60,000   CNN  No sensitivity or
                  [101]
                et al.  lesion                           model to identify   significant, 60,000   specificity given;
                     detection                           multiple lesions on  insignificant   overall detection
                                                         CE and classify   Testing: 20 CE videos  rate of 81.6%
                                                         images based on
                                                         significance
                                                                            [54]   [110]
                Xing    Multiple   2020  Retrospective China  Develop AGDN   CAD-CAP   and KID     CNN  Sensitivity of
                  [102]
               etal.  lesion                             model for WCE   databases used for training   95.72% for
                     detection                           image       and testing              normal, 90.7% for
                                                         classification                       vascular images,
                                                                                              87.44% for
                                                                                              inflammatory
                                                                                              images
                Zhu    Multiple   2021  Retrospective China  Construct new   CAD-CAP [54]  and KID [110]    Deep   Sensitivity of 97%
                  [103]
                etal.  lesion                            deep learning   databases used for training  neural   for normal,
                     detection                           model for   and testing       network 94.17% for
                                                         classification and                   vascular images,
                                                         segmentation of                      92.71% for
                                                         WCE images                           inflammatory
                                                                                              images
                Guo    Multiple   2021  Retrospective China  Utilise CNN   Training: 1,440 images   CNN  Sensitivity of
                etal. [104]  lesion                      models for the   Testing: 360 images  96.67% for
                     detection                           automatic                            vascular lesions,
                                                         detection of                         sensitivity of
                                                         vascular and                         93.33% for
                                                         inflammatory                         inflammatory
                                                         lesions                              lesions
                Goel    Multiple   2022  Retrospective India  Develop CNN   Trained and tested on   CNN  Sensitivity of
                etal. [105]  lesion                      framework to test  collected 7,259 normal   98.06% on
                     detection                           importance of   images and 1,683     collected
                                                         colour features for  abnormal images   database,
                                                         lesion detection  Also trained and tested on   sensitivity of 97%
                                                                     KID [110]  database      on KID
                Yokote  Multiple   2023  Retrospective Japan  Construction of   Training: 17,085 images   CNN  Sensitivity of 91%
                  [106]
                et al.  lesion                           objection detection  Testing: 1,396 images
                     detection                           AI model for
                                                         classification of 12
                                                         types of lesions
                                                         from CE images
                Ding    Multiple   2023  Retrospective China  Development of AI  Training: 280,426 images  CNN  Median sensitivity
                etal. [107]  lesion                      tool to detect   Testing: 240 videos  of 96.25%,
                     detection                           multiple lesion                      median specificity
                                                         types on CE                          of 83.65%
               AI: Artificial intelligence; CNN: convolutional neural network; CE: capsule endoscopy; AGDN: attention guided deformation network; WCE:
               wireless capsule endoscopy; CAD-CAP: computer-assisted diagnosis for capsule endoscopy; KID: koulaouzidis-iakovidis database; SVM: support
               vector machine.

               While AI shows high overall accuracy across many studies, it is important to note that overall accuracy
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