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Monaco et al. J Environ Expo Assess 2024;3:18 https://dx.doi.org/10.20517/jeea.2024.10 Page 15 of 18

Understanding the mechanisms underlying DEHP-induced changes in the gut microbiome and intestinal
structure will be crucial for developing targeted strategies to protect vulnerable populations, such as infants,
from the adverse effects of phthalate exposure.

DECLARATIONS
Authors’ contributions
Made substantial contributions to study conception and design: Donovan SM, Flaws JA, Irudayaraj JM,
Cann I
Performed sample and data analysis and interpretation: Monaco MH, Coyne S, Wang M, Donovan SM
All authors approved the final manuscript.

Availability of data and materials
The datasets generated during the current study are available from the corresponding author upon
reasonable request.

Financial support and sponsorship
Funding was provided by the Microbiome Metabolic Engineering Theme at the Carl R. Woese Institute for
Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL.

Conflicts of interest
All authors declared that there are no conflicts of interest.

Ethical approval and consent to participate
All animal and experimental procedures were approved by the Unversity of Illinois at Urbana-Champaign
Institutional Animal Care and Use Committee (protocol # 18112).

Consent for publication
Not Applicable.

Copyright
© The Author(s) 2024.

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