Page 66 - Read Online
P. 66
Wang et al. Genotoxic NF-kB activation in cancer
Chepelev I, Zhao K. High-resolution profiling of histone methylations 119. Kawagoe T, Takeuchi O, Takabatake Y, Kato H, Isaka Y, Tsujimura T,
in the human genome. Cell 2007;129:823-37. Akira S. TANK is a negative regulator of Toll-like receptor signaling
102. Metzger E, Imhof A, Patel D, Kahl P, Hoffmeyer K, Friedrichs N, and is critical for the prevention of autoimmune nephritis. Nat
Muller JM, Greschik H, Kirfel J, Ji S, Kunowska N, Beisenherz- immunol 2009;10:965-72.
Huss C, Gunther T, Buettner R, Schule R. Phosphorylation of histone 120. Maruyama K, Kawagoe T, Kondo T, Akira S, Takeuchi O. TRAF
H3T6 by PKCbeta(I) controls demethylation at histone H3K4. Nature family member-associated NF-kappaB activator (TANK) is a negative
2010;464:792-6. regulator of osteoclastogenesis and bone formation. J Biol Chem
103. Kanoh J, Francesconi S, Collura A, Schramke V, Ishikawa F, 2012;287:29114-24.
Baldacci G, Geli V. The fission yeast spSet1p is a histone H3-K4 121. Wang W, Huang X, Xin HB, Fu M, Xue A, Wu ZH. TRAF Family
methyltransferase that functions in telomere maintenance and DNA Member-associated NF-kappaB Activator (TANK) Inhibits Genotoxic
repair in an ATM kinase Rad3-dependent pathway. J Mol Biol Nuclear Factor kappaB Activation by Facilitating Deubiquitinase
2003;326:1081-94. USP10-dependent Deubiquitination of TRAF6 Ligase. J Biol Chem
104. Moyal L, Lerenthal Y, Gana-Weisz M, Mass G, So S, Wang SY, 2015;290:13372-85.
Eppink B, Chung YM, Shalev G, Shema E, Shkedy D, Smorodinsky 122. Baldwin AS. Regulation of cell death and autophagy by IKK and
NI, van Vliet N, Kuster B, Mann M, Ciechanover A, Dahm-Daphi NF-kappaB: critical mechanisms in immune function and cancer.
J, Kanaar R, Hu MC, Chen DJ, Oren M, Shiloh Y. Requirement of Immunol Rev 2012;246:327-45.
ATM-dependent monoubiquitylation of histone H2B for timely repair 123. Orlowski RZ, Baldwin AS. NF-kappaB as a therapeutic target in
of DNA double-strand breaks. Mol Cell 2011;41:529-42. cancer. Trends Mol Med 2002;8:385-9.
105. Nakamura K, Kato A, Kobayashi J, Yanagihara H, Sakamoto S, 124. Veuger SJ, Hunter JE, Durkacz BW. Ionizing radiation-induced NF-
Oliveira DV, Shimada M, Tauchi H, Suzuki H, Tashiro S, Zou L, kappaB activation requires PARP-1 function to confer radioresistance.
Komatsu K. Regulation of homologous recombination by RNF20- Oncogene 2009;28:832-42.
dependent H2B ubiquitination. Mol Cell 2011;41:515-28. 125. Bassing CH, Alt FW. The cellular response to general and programmed
106. Sun SC. CYLD: a tumor suppressor deubiquitinase regulating NF- DNA double strand breaks. DNA Repair (Amst) 2004;3:781-96.
kappaB activation and diverse biological processes. Cell Death Differ 126. Lumsden JM, McCarty T, Petiniot LK, Shen R, Barlow C, Wynn
2010;17:25-34. TA, Morse HC 3rd, Gearhart PJ, Wynshaw-Boris A, Max EE, Hodes
107. Zhou L, Azfer A, Niu J, Graham S, Choudhury M, Adamski FM, Younce RJ. Immunoglobulin class switch recombination is impaired in Atm-
C, Binkley PF, Kolattukudy PE. Monocyte chemoattractant protein-1 deficient mice. J Exp Med 2004;200:1111-21.
induces a novel transcription factor that causes cardiac myocyte 127. Slatter MA, Gennery AR. Primary immunodeficiencies associated
apoptosis and ventricular dysfunction. Circ Res 2006;98:1177-85. with DNA-repair disorders. Exp Rev Mol Med 2010;12:e9.
108. Liang J, Wang J, Azfer A, Song W, Tromp G, Kolattukudy PE, Fu M. 128. Lavin MF. Ataxia-telangiectasia: from a rare disorder to a paradigm
A novel CCCH-zinc finger protein family regulates proinflammatory for cell signalling and cancer. Nat Rev Mol Cell Biol 2008;9:759-69.
activation of macrophages. J Biol Chem 2008;283:6337-46. 129. Bredemeyer AL, Helmink BA, Innes CL, Calderon B, McGinnis
109. Liang J, Saad Y, Lei T, Wang J, Qi D, Yang Q, Kolattukudy PE, Fu M. LM, Mahowald GK, Gapud EJ, Walker LM, Collins JB, Weaver
MCP-induced protein 1 deubiquitinates TRAF proteins and negatively BK, Mandik-Nayak L, Schreiber RD, Allen PM, May MJ, Paules
regulates JNK and NF-kappaB signaling. J Exp Med 2010;207:2959-73. RS, Bassing CH, Sleckman BP. DNA double-strand breaks activate a
110. Matsushita K, Takeuchi O, Standley DM, Kumagai Y, Kawagoe multi-functional genetic program in developing lymphocytes. Nature
T, Miyake T, Satoh T, Kato H, Tsujimura T, Nakamura H, Akira S. 2008;456:819-23.
Zc3h12a is an RNase essential for controlling immune responses by 130. Jain A, Ma CA, Liu S, Brown M, Cohen J, Strober W. Specific
regulating mRNA decay. Nature 2009;458:1185-90. missense mutations in NEMO result in hyper-IgM syndrome with
111. Skalniak L, Mizgalska D, Zarebski A, Wyrzykowska P, Koj A, Jura J. hypohydrotic ectodermal dysplasia. Nat Immunol 2001;2:223-8.
Regulatory feedback loop between NF-kappaB and MCP-1-induced 131. Jain A, Ma CA, Lopez-Granados E, Means G, Brady W, Orange JS,
protein 1 RNase. FEBS J 2009;276:5892-905. Liu S, Holland S, Derry JM. Specific NEMO mutations impair CD40-
112. Niu J, Shi Y, Xue J, Miao R, Huang S, Wang T, Wu J, Fu M, Wu mediated c-Rel activation and B cell terminal differentiation. J Clin
ZH. USP10 inhibits genotoxic NF-kappaB activation by MCPIP1- Invest 2004;114:1593-602.
facilitated deubiquitination of NEMO. EMBO J 2013;32:3206-19. 132. Huang TT, Feinberg SL, Suryanarayanan S, Miyamoto S. The zinc
113. Pomerantz JL, Baltimore D. NF-kappaB activation by a signaling finger domain of NEMO is selectively required for NF-kappa B
complex containing TRAF2, TANK and TBK1, a novel IKK-related activation by UV radiation and topoisomerase inhibitors. Mol Cell
kinase. EMBO J 1999;18:6694-704. Biol 2002;22:5813-25.
114. Rothe M, Xiong J, Shu HB, Williamson K, Goddard A, Goeddel DV. 133. Grosjean-Raillard J, Tailler M, Ades L, Perfettini JL, Fabre C, Braun
I-TRAF is a novel TRAF-interacting protein that regulates TRAF- T, De Botton S, Fenaux P, Kroemer G. ATM mediates constitutive NF-
mediated signal transduction. Proc Natl Acad Sci U S A 1996;93:8241-6. kappaB activation in high-risk myelodysplastic syndrome and acute
115. Cheng G, Baltimore D. TANK, a co-inducer with TRAF2 of TNF- and myeloid leukemia. Oncogene 2009;28:1099-109.
CD 40L-mediated NF-kappaB activation. Genes Dev 1996;10:963-73. 134. Keats JJ, Fonseca R, Chesi M, Schop R, Baker A, Chng WJ, Van Wier
116. Sharma S, tenOever BR, Grandvaux N, Zhou GP, Lin R, Hiscott J. S, Tiedemann R, Shi CX, Sebag M, Braggio E, Henry T, Zhu YX,
Triggering the interferon antiviral response through an IKK-related Fogle H, Price-Troska T, Ahmann G, Mancini C, Brents LA, Kumar
pathway. Science 2003;300:1148-51. S, Greipp P, Dispenzieri A, Bryant B, Mulligan G, Bruhn L, Barrett M,
117. Hacker H, Redecke V, Blagoev B, Kratchmarova I, Hsu LC, Wang Valdez R, Trent J, Stewart AK, Carpten J, Bergsagel PL. Promiscuous
GG, Kamps MP, Raz E, Wagner H, Hacker G, Mann M, Karin M. mutations activate the noncanonical NF-kappaB pathway in multiple
Specificity in Toll-like receptor signalling through distinct effector myeloma. Cancer Cell 2007;12:131-44.
functions of TRAF3 and TRAF6. Nature 2006;439:204-7. 135. Meylan E, Dooley AL, Feldser DM, Shen L, Turk E, Ouyang C, Jacks
118. Oganesyan G, Saha SK, Guo B, He JQ, Shahangian A, Zarnegar B, Perry T. Requirement for NF-kappaB signalling in a mouse model of lung
A, Cheng G. Critical role of TRAF3 in the Toll-like receptor-dependent adenocarcinoma. Nature 2009;462:104-7.
and -independent antiviral response. Nature 2006;439:208-11. 136. Boehm JS, Zhao JJ, Yao J, Kim SY, Firestein R, Dunn IF, Sjostrom SK,
58 Journal of Cancer Metastasis and Treatment ¦ Volume 3 ¦ March 27, 2017