Page 64 - Read Online

Cell Biol 2010;188:11-19. 44. Huang H, Colella S, Kurrer M, Yonekawa Y, Kleihues P, Ohgaki H. Gene
21. Cox TR, Erler JT. Remodeling and homeostasis of the extracellular expression profiling of low-grade diffuse astrocytomas by cDNA arrays.
matrix: implications for fibrotic diseases and cancer. Dis Model Mech Cancer Res 2000;60:6868-74.
2011;4:165-78. 45. Bhoopathi P, Gondi CS, Gujrati M, Dinh DH, Lakka SS. SPARC
22. Rusert JM, Wu X, Eberhart CG, Taylor MD, Wechsler-Reya RJ. mediates Src-induced disruption of actin cytoskeleton via inactivation of
SnapShot: Medulloblastoma. Cancer Cell 2014;26:940-40.e1. small GTPases Rho-Rac-Cdc42. Cell Signal 2011;23:1978-87.
23. Brochner CB, Holst CB, Mollgard K. Outer brain barriers in rat and 46. Edwards LA, Woolard K, Son MJ, Li A, Lee J, Ene C, Mantey SA, Maric
human development. Front Neurosci 2015;9:75. D, Song H, Belova G, Jensen RT, Zhang W, Fine HA. Effect of brain- and
24. Saboori P, Sadegh A. Histology and Morphology of the Brain tumor-derived connective tissue growth factor on glioma invasion. J Natl
Subarachnoid Trabeculae. Anat Res Int 2015;2015:279814. Cancer Inst 2011;103:1162-78.
25. Zimmermann DR, Dours-Zimmermann MT. Extracellular matrix of the 47. Klein A, Schwartz H, Sagi-Assif O, Meshel T, Izraely S, Ben Menachem
central nervous system: from neglect to challenge. Histochem Cell Biol S, Bengaiev R, Ben-Shmuel A, Nahmias C, Couraud PO, Witz IP, Erez
2008;130:635-53. N. Astrocytes facilitate melanoma brain metastasis via secretion of IL-23.
26. Zurn AD, Bandtlow CE. Regeneration failure in the CNs: cellular and J Pathol 2015;236 116-27.
molecular mechanisms. Adv Exp Med Biol 2006;557:54-76. 48. Zimmermann M, Box C, Eccles SA. Two-dimensional vs. three-
27. Morgenstern DA, Asher RA, Fawcett JW. Chondroitin sulphate dimensional in vitro tumor migration and invasion assays. Methods Mol
proteoglycans in the CNS injury response. Prog Brain Res 2002;137:313- Biol 2013;986:227-52.
32. 49. Matsusaki M, Case CP, Akashi M. Three-dimensional cell culture
28. Jones EV, Bouvier DS. Astrocyte-secreted matricellular proteins in technique and pathophysiology. Adv Drug Deliv Rev 2014;74:95-103.
CNS remodelling during development and disease. Neural Plast 50. Astashkina A, Grainger DW. Critical analysis of 3-D organoid in vitro cell
2014;2014:321209. culture models for high-throughput drug candidate toxicity assessments.
29. Klekner A, Hutoczki G, Virga J, Remenyi-Puskar J, Toth J, Scholtz B, Ad Drug Deliv Rev 2014;69-70:1-18.
Csősz É, Kalló G, Steiner L, Hortobágyi T, Bognár L. Expression pattern 51. Weigelt B, Ghajar CM, Bissell MJ. The need for complex 3D culture
of invasion-related molecules in the peritumoral brain. Clin Neurol models to unravel novel pathways and identify accurate biomarkers in
Neurosurg 2015;139: 138-43. breast cancer. Ad Drug Deliv Rev 2014;69-70:42-51.
30. Ulrich TA, de Juan Pardo EM, Kumar S. The mechanical rigidity of the 52. Thoma CR, Zimmermann M, Agarkova I, Kelm JM, Krek W. 3D cell
extracellular matrix regulates the structure, motility, and proliferation of culture systems modeling tumor growth determinants in cancer target
glioma cells. Cancer Res 2009;69:4167-74. discovery. Ad Drug Deliv Rev 2014;69-70:29-41.
31. Kim SN, Jeibmann A, Halama K, Witte HT, Walte M, Matzat T, Schillers 53. Hirata E, Yukinaga H, Kamioka Y, Arakawa Y, Miyamoto S, Okada T,
H, Faber C, Senner V, Paulus W, Klämbt C. ECM stiffness regulates Sahai E, Matsuda M. In vivo fluorescence resonance energy transfer
glial migration in Drosophila and mammalian glioma models. Dev imaging reveals differential activation of Rho-family GTPases in
2014;141:3233-42. glioblastoma cell invasion. J Cell Sci 2012;125:858-68.
32. Rao SS, Bentil S, DeJesus J, Larison J, Hissong A, Dupaix R, Sarkar A, 54. Ivanov DP, Parker TL, Walker DA, Alexander C, Ashford MB, Gellert
Winter JO. Inherent interfacial mechanical gradients in 3D hydrogels PR, Garnett MC. In vitro co-culture model of medulloblastoma and
influence tumor cell behaviors. PLoS One 2012;7:e35852. human neural stem cells for drug delivery assessment. J Biotechnol
33. Kim Y, Kumar S. CD44-mediated adhesion to hyaluronic acid contributes 2015;205:3-13.
to mechanosensing and invasive motility. Mol Cancer Res 2014;12:1416- 55. Morfouace M, Shelat A, Jacus M, Freeman BB, 3rd, Turner D, Robinson
29. S, Zindy F, Wang YD, Finkelstein D, Ayrault O, Bihannic L, Puget S,
34. Dvorak HF. Tumors: Wounds That Do Not Heal--Redux. Cancer Imunnol Li XN, Olson JM, Robinson GW, Guy RK, Stewart CF, Gajjar A,
Res 2015;3:1-11. Roussel MF. Pemetrexed and gemcitabine as combination therapy for the
35. Halliday JJ, Holland EC. Connective tissue growth factor and the parallels treatment of Group3 medulloblastoma. Cancer Cell 2014;25:516-29.
between brain injury and brain tumors. J Natl Cancer Inst 2011;103:1141- 56. Kumar KS, Pillong M, Kunze J, Burghardt I, Weller M, Grotzer MA,
3. Schneider G, Baumgartner M. Computer-assisted quantification of motile
36. Yang I, Han SJ, Kaur G, Crane C, Parsa AT. The role of microglia in and invasive capabilities of cancer cells. Sci Rep 2015;5:15338.
central nervous system immunity and glioma immunology. J Clin 57. Ansari N, Muller S, Stelzer EH, Pampaloni F. Quantitative 3D cell-based
Neurosci 2010;17:6-10. assay performed with cellular spheroids and fluorescence microscopy.
37. Charles NA, Holland EC, Gilbertson R, Glass R, Kettenmann H. The Methods Cell Biol 2013;113:295-309.
brain tumor microenvironment. Glia 2011;59:1169-80. 58. Eichler M, Jahnke HG, Krinke D, Muller A, Schmidt S, Azendorf R,
38. Kerber M, Reiss Y, Wickersheim A, Jugold M, Kiessling F, Heil M, Robitzki AA. A novel 96-well multielectrode array based impedimetric
Tchaikovski V, Waltenberger J, Shibuya M, Plate KH, Machein MR. Flt- monitoring platform for comparative drug efficacy analysis on 2D and 3D
1 signaling in macrophages promotes glioma growth in vivo. Cancer Res brain tumor cultures. Biosens Bioelectron 2015;67:582-9.
2008;68:7342-51. 59. Gritsenko PG, Ilina O, Friedl P. Interstitial guidance of cancer invasion. J
39. Strik HM, Stoll M, Meyermann R. Immune cell infiltration of intrinsic Pathol 2012;226:185-99.
and metastatic intracranial tumours. Anticancer Res 2004;24:37-42. 60. Fernandez-Fuente G, Mollinedo P, Grande L, Vazquez-Barquero A,
40. Margol AS, Robison NJ, Gnanachandran J, Hung LT, Kennedy RJ, Vali Fernandez-Luna JL. Culture dimensionality influences the resistance of
M Dhall G, Finlay JL, Erdreich-Epstein A, Krieger MD, Drissi R, Fouladi glioblastoma stem-like cells to multikinase inhibitors. Mol Cancer Ther
M, Gilles FH, Judkins AR, Sposto R, Asgharzadeh S. Tumor-associated 2014;13:1664-72.
macrophages in SHH subgroup of medulloblastomas. Clin Cancer Res 61. Pagliarini R, Shao W, Sellers WR. Oncogene addiction: pathways of
2015;21:1457-65. therapeutic response, resistance, and road maps toward a cure. EMBO
41. Placone AL, Quinones-Hinojosa A, Searson PC. The role of astrocytes Rep 2015;16:280-296.
in the progression of brain cancer: complicating the picture of the tumor 62. Rao S, DeJesus J, Short AR, Otero JJ, Sarkar A, Winter JO. Glioblastoma
microenvironment. Tumour Biol 2015. Behaviors in Three-Dimensional Collagen-Hyaluronan Composite
42. Kim JK, Jin X, Sohn YW, Jin X, Jeon HY, Kim EJ, Ham SW, Jeon HM, Hydrogels. ACS Appl Mate Interfaces 2013;5:9276-84.
Chang SY, Oh SY, Yin J, Kim SH, Park JB, Nakano I, Kim H. Tumoral 63. Florczyk SJ, Wang K, Jana S, Wood DL, Sytsma SK, Sham JG, Kievit
RANKL activates astrocytes that promote glioma cell invasion through FM, Zhang M. Porous chitosan-hyaluronic acid scaffolds as a mimic of
cytokine signaling. Cancer Lett 2014;353:194-200. glioblastoma microenvironment ECM. Biomaterials 2013;34:10143-50.
43. Rath BH, Fair JM, Jamal M, Camphausen K, Tofilon PJ. Astrocytes 64. Pedron S, Becka E, Harley BA. Regulation of glioma cell phenotype in
enhance the invasion potential of glioblastoma stem-like cells. PLoS One 3D matrices by hyaluronic acid. Biomaterials 2013;34:7408-17.
2013;8:e54752. 65. Biggs T, Foreman J, Sundstrom L, Regenass U, Lehembre F. Antitumor

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