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Furthermore, these biomarkers could also been applied for   interface has come tighter and promising. However, the best
            other tumors and even other neurological diseases, without   result will come with the integration between technology
            any contrast addition and increase of costs. [69,70]  for resection and tumor nature knowledge.

            For high-grade lesions with increased neo-vascularization,   Financial support and sponsorship
            there was a report with use of indocyanine  green (ICG)   Nil.
            for detection  of tumor  borders. It  is classically  used by
            ophthalmologists for retinal vasculature and more recently   Conflicts of interest
            for  vascular  neurosurgeries  for  aneurysms  and  arterio-  There are no conflicts of interest.
            venous  malformations;  however,  for  surgical  borders  for
            high-grade gliomas, it is a novel technique.  Eyüpoglu et   REFERENCES
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