Page 68 - Read Online

marker for isolated tumor cells in peripheral blood and bone Gastroenterology 2010;138:1714-26.
marrow in gastric cancer cases. Ann Surg Oncol 2008;15:2934-42. 53. Bork U, Rahbari NN, Scholch S, Reissfelder C, Kahlert C,
39. van de Stolpe A, Pantel K, Sleijfer S, Terstappen LW, Buchler MW, Weitz J, Koch M. Circulating tumour cells and
den Toonder JM. Circulating tumor cell isolation and diagnostics: outcome in non-metastatic colorectal cancer: a prospective
toward routine clinical use. Cancer Res 2011;71:5955-60. study. Br J Cancer 2015;112:1306-13.
40. Klein CA, Blankenstein TJ, Schmidt-Kittler O, Petronio M, 54. Aggarwal C, Meropol NJ, Punt CJ, Iannotti N, Saidman BH,
Polzer B, Stoecklein NH, Riethmuller G. Genetic heterogeneity Sabbath KD, Gabrail NY, Picus J, Morse MA, Mitchell E,
of single disseminated tumour cells in minimal residual cancer. Miller MC, Cohen SJ. Relationship among circulating tumor
Lancet 2002;360:683-9. cells, CEA and overall survival in patients with metastatic
41. Ikeda Y, Mori M, Kamakura T, Haraguchi Y, Saku M, colorectal cancer. Ann Oncol 2013;24:420-8.
Sugimachi K. Increased incidence of undifferentiated type of 55. Matsusaka S, Suenaga M, Mishima Y, Kuniyoshi R, Takagi K,
gastric cancer with tumor progression in 912 patients with Terui Y, Mizunuma N, Hatake K. Circulating tumor cells as a
early gastric cancer and 1245 with advanced gastric cancer. surrogate marker for determining response to chemotherapy in
Cancer 1994;73:2459-63. Japanese patients with metastatic colorectal cancer. Cancer Sci
42. Kaganoi J, Shimada Y, Kano M, Okumura T, Watanabe G, 2011;102:1188-92.
Imamura M. Detection of circulating oesophageal squamous 56. Sastre J, Maestro ML, Gomez-Espana A, Rivera F,
cancer cells in peripheral blood and its impact on prognosis. Valladares M, Massuti B, Benavides M, Gallen M, Marcuello E,
Br J Surg 2004;91:1055-60. Abad A, Arrivi A, Fernandez-Martos C, Gonzalez E,
43. Liu Z, Jiang M, Zhao J, Ju H. Circulating tumor cells in Tabernero JM, Vidaurreta M, Aranda E, Diaz-Rubio E.
perioperative esophageal cancer patients: quantitative assay system Circulating tumor cell count is a prognostic factor in metastatic
and potential clinical utility. Clin Cancer Res 2007;13:2992-7. colorectal cancer patients receiving fi rst-line chemotherapy plus
44. Setoyama T, Natsugoe S, Okumura H, Matsumoto M, bevacizumab: a Spanish Cooperative Group for the Treatment
Uchikado Y, Ishigami S, Owaki T, Takao S, Aikou T. of Digestive Tumors study. Oncologist 2012;17:947-55.
Carcinoembryonic antigen messenger RNA expression in 57. Tol J, Koopman M, Miller MC, Tibbe A, Cats A, Creemers GJ,
blood predicts recurrence in esophageal cancer. Clin Cancer Vos AH, Nagtegaal ID, Terstappen LW, Punt CJ. Circulating
Res 2006;12:5972-7. tumour cells early predict progression-free and overall
45. Tanaka K, Yano M, Motoori M, Kishi K, Miyashiro I, survival in advanced colorectal cancer patients treated with
Shingai T, Gotoh K, Noura S, Takahashi H, Ohue M, chemotherapy and targeted agents. Ann Oncol 2010;21:1006-12.
Yamada T, Ohigashi H, Yamamoto T, Yamasaki T, Doki Y, 58. Yen LC, Yeh YS, Chen CW, Wang HM, Tsai HL, Lu CY,
Ishikawa O. CEA-antigen and SCC-antigen mRNA expression Chang YT, Chu KS, Lin SR, Wang JY. Detection of KRAS
in peripheral blood predict hematogenous recurrence after oncogene in peripheral blood as a predictor of the response
resection in patients with esophageal cancer. Ann Surg Oncol to cetuximab plus chemotherapy in patients with metastatic
2010;17:2779-86. colorectal cancer. Clin Cancer Res 2009;15:4508-13.
46. Matsushita D, Uenosono Y, Arigami T, Yanagita S, Nishizono Y, 59. Gasch C, Bauernhofer T, Pichler M, Langer-Freitag S, Reeh M,
Hagihara T, Hirata M, Haraguchi N, Arima H, Kijima Y, Seifert AM, Mauermann O, Izbicki JR, Pantel K, Riethdorf S.
Kurahara H, Maemura K, Okumura H, Ishigami S, Natsugoe S. Heterogeneity of epidermal growth factor receptor status and
Clinical signifi cance of circulating tumor cells in peripheral mutations of KRAS/PIK3CA in circulating tumor cells of
blood of patients with esophageal squamous cell carcinoma. patients with colorectal cancer. Clin Chem 2013;59:252-60.
Ann Surg Oncol 2015. doi: 10.1245/s10434-015-4392-8. 60. Pantel K, Brakenhoff RH, Brandt B. Detection, clinical
47. Reeh M, Effenberger KE, Koenig AM, Riethdorf S, relevance and specifi c biological properties of disseminating
Eichstadt D, Vettorazzi E, Uzunoglu FG, Vashist YK, tumour cells. Nat Rev Cancer 2008;8:329-40.
Izbicki JR, Pantel K, Bockhorn M. Circulating tumor cells 61. Braun S, Pantel K, Muller P, Janni W, Hepp F, Kentenich CR,
as a biomarker for preoperative prognostic staging in patients Gastroph S, Wischnik A, Dimpfl T, Kindermann G,
with esophageal cancer. Ann Surg 2015;261:1124-30. Riethmuller G, Schlimok G. Cytokeratin-positive cells in the
48. Huang X, Gao P, Song Y, Sun J, Chen X, Zhao J, Xu H, bone marrow and survival of patients with stage I, II, or III
Wang Z. Meta-analysis of the prognostic value of circulating breast cancer. N Engl J Med 2000;342:525-33.
tumor cells detected with the CellSearch System in colorectal 62. Yang J, Weinberg RA. Epithelial-mesenchymal transition: at
cancer. BMC Cancer 2015;15:202. the crossroads of development and tumor metastasis. Dev Cell
49. Wang S, Zheng G, Cheng B, Chen F, Wang Z, Chen Y, Wang Y, 2008;14:818-29.
Xiong B. Circulating tumor cells (CTCs) detected by RT-PCR 63. Wu S, Liu S, Liu Z, Huang J, Pu X, Li J, Yang D, Deng H,
and its prognostic role in gastric cancer: a meta-analysis of Yang N, Xu J. Classifi cation of circulating tumor cells
published literature. PLoS One 2014;9:e99259. by epithelial-mesenchymal transition markers. PLoS One
50. Zhang ZY, Dai ZL, Yin XW, Li SH, Li SP, Ge HY. 2015;10:e0123976.
Meta-analysis shows that circulating tumor cells including 64. Iinuma H, Watanabe T, Mimori K, Adachi M, Hayashi N,
circulating microRNAs are useful to predict the survival of Tamura J, Matsuda K, Fukushima R, Okinaga K, Sasako M,
patients with gastric cancer. BMC Cancer 2014;14:773. Mori M. Clinical signifi cance of circulating tumor cells,
51. Tang L, Zhao S, Liu W, Parchim NF, Huang J, Tang Y, including cancer stem-like cells, in peripheral blood for
Gan P, Zhong M. Diagnostic accuracy of circulating tumor recurrence and prognosis in patients with Dukes’ stage B and
cells detection in gastric cancer: systematic review and C colorectal cancer. J Clin Oncol 2011;29:1547-55.
meta-analysis. BMC Cancer 2013;13:314. 65. Pilati P, Mocellin S, Bertazza L, Galdi F, Briarava M,
52. Rahbari NN, Aigner M, Thorlund K, Mollberg N, Motschall E, Mammano E, Tessari E, Zavagno G, Nitti D. Prognostic value
Jensen K, Diener MK, Buchler MW, Koch M, Weitz J. of putative circulating cancer stem cells in patients undergoing
Meta-analysis shows that detection of circulating tumor cells hepatic resection for colorectal liver metastasis. Ann Surg
indicates poor prognosis in patients with colorectal cancer. Oncol 2012;19:402-8.

Journal of Cancer Metastasis and Treatment ¦ Volume 1 ¦ Issue 3 ¦ October 15, 2015 ¦ 137