Page 25 - Read Online
P. 25

association with poor prognosis in head and neck cancer. Head   122. Conklin  KA.  Chemotherapy-associated  oxidative  stress:
               Neck 2015;37:727-34.                               impact on chemotherapeutic effectiveness. Integr Cancer Ther
              105. Onodera  Y,  Motohashi  H,  Takagi  K,  Miki  Y,  Shibahara  Y,   2004;3:294-300.
               Watanabe M, Ishida T, Hirakawa H, Sasano H, Yamamoto M,       123. Sullivan  LB,  Chandel  NS.  Mitochondrial  reactive  oxygen
               Suzuki  T.  NRF2  immunolocalization  in  human  breast   species and cancer. Cancer Metab 2014;2:17.
               cancer  patients  as  a  prognostic  factor.  Endocr Relat Cancer   124. Raj  L,  Ide  T,  Gurkar  AU,  Foley  M,  Schenone  M,  Li  X,
               2014;21:241-52.                                    Tolliday  NJ,  Golub  TR,  Carr  SA,  Shamji  AF,  Stern  AM,
            106. Soini  Y,  Eskelinen  M,  Juvonen  P,  Karja  V,  Haapasaari  KM,   Mandinova  A,  Schreiber  SL,  Lee  SW.  Selective  killing  of
               Saarela A, Karihtala P. Nuclear Nrf2 expression is related to a   cancer cells by a small molecule targeting the stress response
               poor survival in pancreatic adenocarcinoma. Pathol Res Pract   to ROS. Nature 2011;475:231-4.
               2014;210:35-9.                                     125. Trachootham  D,  Zhou  Y,  Zhang  H,  Demizu  Y,  Chen  Z,
                107. Kawasaki Y, Ishigami S, Arigami T, Uenosono Y, Yanagita S,   Pelicano  H,  Chiao  PJ,  Achanta  G,  Arlinghaus  RB,  Liu  J,
               Uchikado  Y,  Kita  Y,  Nishizono  Y,  Okumura  H,  Nakajo  A,   Huang  P.  Selective  killing  of  oncogenically  transformed  cells
               Kijima  Y,  Maemura  K,  Natsugoe  S.  Clinicopathological   through  a  ROS-mediated  mechanism  by  beta-phenylethyl
               signifi cance  of  nuclear  factor  (erythroid-2)-related  factor   isothiocyanate. Cancer Cell 2006;10:241-52.
               2 (Nrf2) expression in gastric cancer. BMC Cancer 2015;15:5.  126. Sawayama  H,  Ishimoto  T,  Watanabe  M,  Yoshida  N,
            108. Yang Y,  Cai  X, Yang  J,  Sun  X,  Hu  C, Yan  Z,  Xu  X,  Lu  W,   Sugihara  H,  Kurashige  J,  Hirashima  K,  Iwatsuki  M,  Baba Y,
               Wang X, Cao P. Chemoprevention of dietary digitofl avone on   Oki E, Morita M, Shiose Y, Baba H. Small molecule agonists
               colitis-associated  colon  tumorigenesis  through  inducing  Nrf2   of  PPAR-gamma  exert  therapeutic  effects  in  esophageal
               signaling pathway and inhibition of infl ammation. Mol Cancer   cancer. Cancer Res 2014;74:575-85.
               2014;13:48.                                        127. Cao X, Fang L, Gibbs S, Huang Y, Dai Z, Wen P, Zheng X,
                109. Kawasaki  Y,  Okumura  H,  Uchikado  Y,  Kita  Y,  Sasaki  K,   Sadee  W,  Sun  D.  Glucose  uptake  inhibitor  sensitizes  cancer
               Owaki T, Ishigami S, Natsugoe S. Nrf2 is useful for predicting   cells  to  daunorubicin  and  overcomes  drug  resistance  in
               the effect of chemoradiation therapy on esophageal squamous   hypoxia. Cancer Chemother Pharmacol 2007;59:495-505.
               cell carcinoma. Ann Surg Oncol 2014;21:2347-52.  128. Wu CH, Ho YS, Tsai CY, Wang YJ, Tseng H, Wei PL, Lee CH,
            110. Andreyev  AY,  Kushnareva  YE,  Starkov  AA.  Mitochondrial   Liu RS, Lin SY. In vitro and in vivo study of phloretin-induced
               metabolism  of  reactive  oxygen  species.  Biochemistry (Mosc)   apoptosis  in  human  liver  cancer  cells  involving  inhibition  of
               2005;70:200-14.                                    type II glucose transporter. Int J Cancer 2009;124:2210-9.
                111. Trachootham D, Alexandre J, Huang P. Targeting cancer cells       129. Liu  Y,  Cao  Y,  Zhang  W,  Bergmeier  S,  Qian  Y,  Akbar  H,
               by ROS-mediated mechanisms: a radical therapeutic approach?   Colvin  R,  Ding  J,  Tong  L,  Wu  S,  Hines  J,  Chen  X.
               Nat Rev Drug Discov 2009;8:579-91.                 A  small-molecule  inhibitor  of  glucose  transporter  1
            112. Klaunig  JE,  Kamendulis  LM.  The  role  of  oxidative  stress  in   downregulates  glycolysis,  induces  cell-cycle  arrest,  and
               carcinogenesis. Annu Rev Pharmacol Toxicol 2004;44:239-67.  inhibits  cancer  cell  growth in vitro  and  in vivo.  Mol Cancer
                113. Sullivan  R,  Graham  CH.  Chemosensitization  of  cancer  by   Ther 2012;11:1672-82.
               nitric oxide. Curr Pharm Des 2008;14:1113-23.  130. Ganapathy-Kanniappan  S,  Vali  M,  Kunjithapatham  R,
            114. Chen EI, Hewel J, Krueger JS, Tiraby C, Weber MR, Kralli A,   Buijs  M,  Syed  LH,  Rao  PP,  Ota  S,  Kwak  BK,  Loffroy  R,
               Becker  K,  Yates  JR  3rd,  Felding-Habermann  B.  Adaptation   Geschwind JF. 3-bromopyruvate: a new targeted antiglycolytic
               of  energy  metabolism  in  breast  cancer  brain  metastases.   agent  and  a  promise  for  cancer  therapy.  Curr Pharm
               Cancer Res 2007;67:1472-86.                        Biotechnol 2010;11:510-7.
            115. Young  TW,  Mei  FC,  Yang  G,  Thompson-Lanza  JA,  Liu  J,       131. Zhou  Y,  Tozzi  F,  Chen  J,  Fan  F,  Xia  L,  Wang  J,  Gao  G,
               Cheng  X. Activation  of  antioxidant  pathways  in  ras-mediated   Zhang  A,  Xia  X,  Brasher  H,  Widger  W,  Ellis  LM,
               oncogenic  transformation  of  human  surface  ovarian  epithelial   Weihua  Z.  Intracellular ATP  levels  are  a  pivotal  determinant
               cells revealed by functional proteomics and mass spectrometry.   of  chemoresistance  in  colon  cancer  cells.  Cancer Res
               Cancer Res 2004;64:4577-84.                        2012;72:304-14.
            116. Xia C, Meng Q, Liu LZ, Rojanasakul Y, Wang XR, Jiang BH.   132. Yu SJ, Yoon JH, Yang JI, Cho EJ, Kwak MS, Jang ES, Lee JH,
               Reactive  oxygen  species  regulate  angiogenesis  and  tumor   Kim  YJ,  Lee  HS,  Kim  CY.  Enhancement  of  hexokinase  II
               growth through vascular endothelial growth factor. Cancer Res   inhibitor-induced  apoptosis  in  hepatocellular  carcinoma
               2007;67:10823-30.                                  cells  via  augmenting  ER  stress  and  anti-angiogenesis  by
                117. Kondoh  H,  Lleonart  ME,  Bernard  D,  Gil  J.  Protection  from   protein  disulfi de  isomerase  inhibition.  J  Bioenerg Biomembr
               oxidative stress by enhanced glycolysis; a possible mechanism   2012;44:101-15.
               of cellular immortalization. Histol Histopathol 2007;22:85-90.      133. Tong  J,  Xie  G,  He  J,  Li  J,  Pan  F,  Liang  H.  Synergistic
            118. Pervaiz S, Clement MV. Tumor intracellular redox status and   antitumor  effect  of  dichloroacetate  in  combination  with
               drug  resistance-Serendipity  or  a  causal  relationship?  Curr   5-fl uorouracil  in  colorectal  cancer.  J  Biomed Biotechnol
               Pharm Des 2004;10:1969-77.                         2011;2011:740564.
                119. Tiligada  E.  Chemotherapy:  induction  of  stress  responses.   134. Shen YC, Ou DL, Hsu C, Lin KL, Chang CY, Lin CY, Liu SH,
               Endocr Relat Cancer 2006;13 Suppl 1:S115-24.       Cheng AL. Activating oxidative phosphorylation by a pyruvate
            120. Hwang  PM,  Bunz  F,  Yu  J,  Rago  C,  Chan  TA,   dehydrogenase kinase inhibitor overcomes sorafenib resistance
               Murphy  MP,  Kelso  GF,  Smith  RA,  Kinzler  KW,   of hepatocellular carcinoma. Br J Cancer 2013;108:72-81.
               Vogelstein  B.  Ferredoxin  reductase  affects  p53-dependent,       135. Miskimins WK, Ahn  HJ,  Kim  JY,  Ryu  S,  Jung YS,  Choi  JY.
               5-fluorouracil-induced  apoptosis  in  colorectal  cancer  cells.   Synergistic  anti-cancer  effect  of  phenformin  and  oxamate.
               Nat Med 2001;7:1111-7.                             PLoS One 2014;9:e85576.
                121. Hwang IT, Chung YM, Kim JJ, Chung JS, Kim BS, Kim HJ,   136. Kim  TH,  Hur  EG,  Kang  SJ,  Kim  JA,  Thapa  D,  Lee  YM,
               Kim  JS, Yoo YD.  Drug  resistance  to  5-FU  linked  to  reactive   Ku SK, Jung Y, Kwak MK. NRF2 blockade suppresses colon
               oxygen  species  modulator  1.  Biochem Biophys Res Commun   tumor  angiogenesis  by  inhibiting  hypoxia-induced  activation
               2007;359:304-10.                                   of HIF-1alpha. Cancer Res 2011;71:2260-75.

                Journal of Cancer Metastasis and Treatment  ¦  Volume 1 ¦ Issue 3 ¦ October 15, 2015 ¦    181
   20   21   22   23   24   25   26   27   28   29   30