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               review. We regret not being able to cite the work published by many others due to the limitation of length.
               Graphics programs available from BioRender.com were used by the authors to design and create Figure 1.

               Authors’ contributions
               Conception and design: Lee WK, Cheng SY
               Writing, review, and revision: Lee WK, Cheng SY

               Availability of data and materials
               No applicable.


               Financial support and sponsorship
               Our research was supported by the Intramural Research Program of the Center for Cancer Research,
               National Cancer Institute, National Institutes of Health (ZIA BC 011191).

               Conflicts of interest
               Both authors declared that there are no conflicts of interest.

               Ethical approval and consent to participate
               Not applicable.


               Consent for publication
               Not applicable.

               Copyright
               ©The Author(s) 2021.


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