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Magee et al.                                                                                                                                                                           Egr1 in liver metabolism and cancer

           sensitivity to chemotherapeutics could be applied   Ethics approval
           as a novel approach for HCC therapy. In addition,   Not applicable.
           whether the current discrepancies on Egr1 function in
           HCC could be due to a dual role of Egr1 during HCC   REFERENCES
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           DECLARATIONS                                       12.  Zhang Y, Xu N, Xu J, Kong B, Copple B, Guo GL, Wang L. E2F1 is
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           Authors’ contributions                             13.  Zhu HY, Bai WD, Wang HT, Xie ST, Tao K, Su LL, Liu JQ, Yang
           Reviewed the literature and wrote the manuscript: N.   XK, Li J, Wang YC, He T, Han JT, Hu DH. Peroxisome proliferator-
           Magee, Y. Zhang                                       activated  receptor-gamma  agonist  inhibits  collagen  synthesis  in
                                                                 human keloid fibroblasts by suppression of early growth response-1
           Financial support and sponsorship                     expression through upregulation of miR-543 expression. Am J Cancer
                                                                 Res 2016;6:1358-70.
           This work was supported by the National Institutes   14.  Dussmann P, Pagel JI, Vogel S, Magnusson T, Zimmermann  R,
           of Health grants NCIK22CA184146, P20GM103549,         Wagner E, Schaper W, Ogris M, Deindl E. Live in vivo imaging
           P20GM103418, P30GM118247, and T32ES007079.            of Egr-1 promoter activity  during neonatal  development,  liver
                                                                 regeneration and wound healing. BMC Dev Biol 2011;11:28.
           Conflicts of Interest                              15.  Christy B, Nathans D. DNA binding site of the growth factor-inducible
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                                                              16.  Fagerberg  L,  Hallstrom  BM, Oksvold P, Kampf  C, Djureinovic
                                                                 D, Odeberg J, Habuka M, Tahmasebpoor S, Danielsson A, Edlund
           Patient consent                                       K, Asplund A, Sjostedt E, Lundberg E, Szigyarto CA, Skogs  M,
           Not applicable.                                       Takanen JO, Berling H, Tegel H, Mulder J, Nilsson P, Schwenk JM,
            274                                                                                                     Hepatoma Research ¦ Volume 3 ¦ November 20, 2017
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