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Magee et al.                                                                                                                                                                           Egr1 in liver metabolism and cancer

               Lindskog C, Danielsson F, Mardinoglu A, Sivertsson A, von Feilitzen   A, O’Brien RM. A phorbol ester-insensitive AP-1 motif mediates the
               K, Forsberg M, Zwahlen M, Olsson I, Navani S, Huss M, Nielsen J,   stimulatory effect of insulin on rat malic enzyme gene transcription.
               Ponten F, Uhlen M. Analysis of the human tissue-specific expression   Mol Endocrinol 1998;12:1778-91.
               by genome-wide integration  of transcriptomics  and antibody-based   34.  Kilbourne EJ, Widom R, Harnish DC,  Malik S,  Karathanasis SK.
               proteomics. Mol Cell Proteomics 2014;13:397-406.  Involvement of early growth response factor Egr-1 in apolipoprotein
           17.  Yang H, Lee  JH, Noh JK, Kim HC, Park CJ, Park JW, Kim KK.   AI gene transcription. J Biol Chem 1995;270:7004-10.
               Expression  pattern  of  early  growth  response gene  1 during  olive   35.  Shen N, Yu X, Pan FY, Gao X, Xue B, Li CJ. An early response
               flounder  (paralichthys  olivaceus)  embryonic  development.  Dev   transcription factor, Egr-1, enhances insulin resistance in type 2
               Reprod 2014;18:233-40.                            diabetes with chronic hyperinsulinism. J Biol Chem 2011;286:14508-
           18.  Pritchard MT, Malinak RN, Nagy LE. Early growth response (EGR)-  15.
               1 is required for timely cell-cycle entry and progression in hepatocytes   36.  Biddinger SB, Kahn CR. From mice to men: insights into the insulin
               after acute  carbon tetrachloride  exposure in mice.  Am J Physiol   resistance syndromes. Annu Rev Physiol 2006;68:123-58.
               Gastrointest Liver Physiol 2011;300:G1124-31.  37.  Fujishiro M, Gotoh Y, Katagiri H, Sakoda H, Ogihara T, Anai M,
           19.  Veyrac A, Gros A, Bruel-Jungerman E, Rochefort C, Kleine Borgmann   Onishi  Y,  Ono H, Abe  M, Shojima  N, Fukushima  Y, Kikuchi  M,
               FB, Jessberger S, Laroche S. Zif268/egr1 gene controls the selection,   Oka Y, Asano T. Three  mitogen-activated  protein  kinases inhibit
               maturation and functional integration of adult hippocampal newborn   insulin signaling by different mechanisms in 3T3-L1 adipocytes. Mol
               neurons by learning. Proc Natl Acad Sci U S A 2013;110:7062-7.  Endocrinol 2003;17:487-97.
           20.  Zhang J, Zhang Y, Sun T, Guo F, Huang S, Chandalia M, Abate N,   38.  Virolle T, Adamson ED, Baron V, Birle D, Mercola D, Mustelin T, de
               Fan D, Xin HB, Chen YE, Fu M. Dietary obesity-induced Egr-1 in   Belle I. The Egr-1 transcription factor directly activates PTEN during
               adipocytes facilitates energy storage via suppression of FOXC2. Sci   irradiation-induced signalling. Nat Cell Biol 2001;3:1124-8.
               Rep 2013;3:1476.                               39.  Shen N, Gong T, Wang JD, Meng FL, Qiao L, Yang RL, Xue B, Pan
           21.  Yang YM, Fang F, Li X, Yu L, Wang ZC. TRAIL overexpression   FY, Zhou XJ, Chen HQ, Ning W, Li CJ. Cigarette smoke-induced
               co-regulated by Egr1 and HRE enhances radiosensitivity of hypoxic   pulmonary inflammatory responses are mediated by EGR-1/GGPPS/
               A549 cells  depending  on its  apoptosis  inducing  role.  Oncol Rep   MAPK signaling. Am J Pathol 2011;178:110-8.
               2017;37:533-9.                                 40.  Yu X, Shen N, Zhang ML, Pan FY, Wang C, Jia WP, Liu C, Gao Q,
           22.  Bhattacharyya S, Wu M, Fang F, Tourtellotte W, Feghali-Bostwick C,   Gao X, Xue B, Li CJ. Egr-1 decreases adipocyte insulin sensitivity
               Varga J. Early growth response transcription factors: key mediators   by tilting  PI3K/Akt and MAPK  signal balance  in mice.  EMBO J
               of  fibrosis  and  novel  targets  for  anti-fibrotic  therapy.  Matrix  Biol   2011;30:3754-65.
               2011;30:235-42.                                41.  Weng K, Hu H, Xu AG, Khaitovich P, Somel M. Mechanisms of
           23.  Kobayashi  D, Yamada  M, Kamagata  C,  Kaneko  R,  Tsuji  N,   dietary response in mice and primates: a role for EGR1 in regulating
               Nakamura  M, Yagihashi A, Watanabe  N. Overexpression of early   the  reaction  to  human-specific  nutritional  content.  PLoS One
               growth response-1 as a metastasis-regulatory factor in gastric cancer.   2012;7:e43915.
               Anticancer Res 2002;22:3963-70.                42.  McMullen MR, Pritchard MT, Wang Q, Millward CA, Croniger CM,
           24.  Gokey NG,  Lopez-Anido C, Gillian-Daniel  AL, Svaren J. Early   Nagy LE.  Early  growth response-1 transcription  factor  is essential
               growth response 1 (Egr1) regulates cholesterol biosynthetic  gene   for ethanol-induced fatty  liver  injury  in  mice. Gastroenterology
               expression. J Biol Chem 2011;286:29501-10.        2005;128:2066-76.
           25.  Mohn KL, Laz TM, Melby AE, Taub R. Immediate-early  gene   43.  Song H, Zheng  Z, Wu J, Lai  J, Chu Q, Zheng  X. White  pitaya
               expression differs between regenerating  liver, insulin-stimulated   (hylocereus undatus) juice attenuates insulin resistance and hepatic
               H-35 cells, and mitogen-stimulated Balb/c 3T3 cells. Liver-specific   steatosis in diet-induced obese mice. PLoS One 2016;11:e0149670.
               induction patterns of gene 33, phosphoenolpyruvate carboxykinase,   44.  Ference BA, Ginsberg HN, Graham I, Ray KK, Packard CJ, Bruckert
               and the jun, fos, and egr families. J Biol Chem 1990;265:21914-21.  E, Hegele RA, Krauss RM, Raal FJ, Schunkert H, Watts GF, Boren
           26.  Rui L. Energy metabolism in the liver. Compr Physiol 2014;4:177-97.  J, Fazio S, Horton JD, Masana L, Nicholls SJ, Nordestgaard BG, van
           27.  Bechmann LP, Hannivoort RA, Gerken G, Hotamisligil GS, Trauner   de Sluis B, Taskinen MR, Tokgozoglu L, Landmesser U, Laufs U,
               M, Canbay A. The interaction of hepatic lipid and glucose metabolism   Wiklund O, Stock JK, Chapman MJ, Catapano  AL. Low-density
               in liver diseases. J Hepatol 2012;56:952-64.      lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence
           28.  Josefsen K, Sorensen LR, Buschard K, Birkenbach  M. Glucose   from genetic,  epidemiologic,  and clinical  studies. A consensus
               induces early growth response gene (Egr-1) expression in pancreatic   statement  from the European Atherosclerosis Society Consensus
               beta cells. Diabetologia 1999;42:195-203.         Panel. Eur Heart J 2017;38:2459-72.
           29.  Hasan RN, Phukan S, Harada S. Differential  regulation  of early   45.  Li T, Chiang JY. Regulation of bile acid and cholesterol metabolism
               growth response gene-1 expression by insulin and glucose in vascular   by PPARs. PPAR Res 2009;2009:501739.
               endothelial cells. Arterioscler Thromb Vasc Biol 2003;23:988-93.  46.  Madison  BB.  Srebp2:  a  master  regulator  of  sterol  and  fatty  acid
           30.  Harada S, Esch GL, Holgado-Madruga M, Wong AJ. Grb-2-associated   synthesis. J Lipid Res 2016;57:333-5.
               binder-1 is involved in insulin-induced egr-1 gene expression through   47.  Sanchez-Infantes D, White UA, Elks CM, Morrison RF, Gimble JM,
               its phosphatidylinositol  3’-kinase  binding site.  DNA Cell  Biol   Considine RV, Ferrante AW, Ravussin E, Stephens JM. Oncostatin m
               2001;20:223-9.                                    is produced in adipose tissue and is regulated in conditions of obesity
           31.  Gousseva N, Kugathasan K, Chesterman  CN, Khachigian  LM.   and type 2 diabetes. J Clin Endocrinol Metab 2014;99:E217-25.
               Early growth response factor-1 mediates insulin-inducible  vascular   48.  Zhou  Y, Zhang F, Abidi  P, Lin  M, Thiel  G, Liu  J. Blockage  of
               endothelial cell proliferation and regrowth after injury. J Cell Biochem   oncostatin M-induced LDL receptor gene transcription by a dominant-
               2001;81:523-34.                                   negative mutant of C/EBPbeta. Biochem J 2006;397:101-8.
           32.  Barroso I, Santisteban P. Insulin-induced early growth response gene   49.  Zhang  F,  Ahlborn  TE,  Li  C,  Kraemer  FB,  Liu  J.  Identification  of
               (Egr-1) mediates a short term repression of rat malic enzyme gene   Egr1 as the oncostatin M-induced transcription activator that binds
               transcription. J Biol Chem 1999;274:17997-8004.   to  sterol-independent  regulatory  element  of human  LDL  receptor
           33.  Streeper RS, Chapman SC, Ayala JE, Svitek CA, Goldman JK, Cave   promoter. J Lipid Res 2002;43:1477-85.
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