Page 145 - Read Online
P. 145
Zhu et al. Function of Mcl-1 and its regulative relations with HCC
Ethics approval of its binding by proapoptotic BH3-only ligands. J Biol Chem
2005;280:4738-44.
Not applicable. 18. Perciavalle RM, Stewart DP, Koss B, Lynch J, Milasta S, Bathina M,
Temirov J, Cleland MM, Pelletier S, Schuetz JD, Youle RJ, Green DR,
REFERENCES Opferman JT. Anti-apoptotic MCL-1 localizes to the mitochondrial
matrix and couples mitochondrial fusion to respiration. Nat Cell Biol
1. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global 2012;14:575-83.
cancer statistics. CA Cancer J Clin 2011;61:69-90. 19. Germain M, Duronio V. The N terminus of the anti-apoptotic BCL-
2. Burroughs A, Hochhauser D, Meyer T. Systemic treatment and 2 homologue MCL-1 regulates its localization and function. J Biol
liver transplantation for hepatocellular carcinoma: two ends of the Chem 2007;282:32233-42.
therapeutic spectrum. Lancet Oncol 2004;5:409-18. 20. Chou CH, Lee RS, Yang-Yen HF. An internal EELD domain
3. Marrero JA, Kudo M, Bronowicki JP. The challenge of prognosis and facilitates mitochondrial targeting of Mcl-1 via a Tom70-dependent
staging for hepatocellular carcinoma. Oncologist 2010;15 Suppl 4:23- pathway. Mol Biol Cell 2006;17:3952-63.
33. 21. Akgul C, Moulding DA, White MR, Edwards SW. In vivo localisation
4. Zheng Y, Gery S, Sun H, Shacham S, Kauffman M, Koeffler HP. KPT- and stability of human Mcl-1 using green fluorescent protein (GFP)
330 inhibitor of XPO1-mediated nuclear export has anti-proliferative fusion proteins. FEBS Lett 2000;478:72-6.
activity in hepatocellular carcinoma. Cancer Chemother Pharmacol 22. Han J, Goldstein LA, Hou W, Rabinowich H. Functional linkage
2014;74:487-95. between NOXA and Bim in mitochondrial apoptotic events. J Biol
5. Kang MH, Reynolds CP. Bcl-2 inhibitors: targeting mitochondrial Chem 2007;282:16223-31.
apoptotic pathways in cancer therapy. Clin Cancer Res 2009;15:1126- 23. Shieh JJ, Liu KT, Huang SW, Chen YJ, Hsieh TY. Modification of
32. alternative splicing of Mcl-1 pre-mRNA using antisense morpholino
6. Hiraki M, Suzuki Y, Alam M, Hinohara K, Hasegawa M, Jin C, oligonucleotides induces apoptosis in basal cell carcinoma cells. J
Kharbanda S, Kufe D. MUC1-C stabilizes MCL-1 in the oxidative Invest Dermatol 2009;129:2497-506.
stress response of triple-negative breast cancer cells to BCL-2 24. Kim JH, Bae J. MCL-1ES induces MCL-1L-dependent BAX- and
inhibitors. Sci Rep 2016;6:26643. BAK-independent mitochondrial apoptosis. PLoS One 2013;8:e79626.
7. Wuilleme-Toumi S, Robillard N, Gomez P, Moreau P, Le Gouill 25. Li P, Guo W, Du L, Zhao J, Wang Y, Liu L, Hu Y, Hou Y. microRNA-
S, Avet-Loiseau H, Harousseau JL, Amiot M, Bataille R. Mcl-1 is 29b contributes to pre-eclampsia through its effects on apoptosis,
overexpressed in multiple myeloma and associated with relapse and invasion and angiogenesis of trophoblast cells. Clin Sci (Lond)
shorter survival. Leukemia 2005;19:1248-52. 2013;124:27-40.
8. Cho-Vega JH, Rassidakis GZ, Admirand JH, Oyarzo M, Ramalingam 26. Palve V, Mallick S, Ghaisas G, Kannan S, Teni T. Overexpression
P, Paraguya A, McDonnell TJ, Amin HM, Medeiros LJ. MCL- of Mcl-1L splice variant is associated with poor prognosis and
1 expression in B-cell non-Hodgkin’s lymphomas. Hum Pathol chemoresistance in oral cancers. PLoS One 2014;9:e111927.
2004;35:1095-100. 27. Legartova S, Krejci J, Harnicarova A, Hajek R, Kozubek S, Bartova
9. Shimazu T, Degenhardt K, Nur EKA, Zhang J, Yoshida T, Zhang E. Nuclear topography of the 1q21 genomic region and Mcl-1
Y, Mathew R, White E, Inouye M. NBK/BIK antagonizes MCL-1 protein levels associated with pathophysiology of multiple myeloma.
and BCL-XL and activates BAK-mediated apoptosis in response to Neoplasma 2009;56:404-13.
protein synthesis inhibition. Genes Dev 2007;21:929-41. 28. Leuenroth SJ, Grutkoski PS, Ayala A, Simms HH. The loss of Mcl-
10. Sieghart W, Losert D, Strommer S, Cejka D, Schmid K, Rasoul- 1 expression in human polymorphonuclear leukocytes promotes
Rockenschaub S, Bodingbauer M, Crevenna R, Monia BP, Peck- apoptosis. J Leukoc Biol 2000;68:158-66.
Radosavljevic M, Wacheck V. Mcl-1 overexpression in hepatocellular 29. Fujise K, Zhang D, Liu J, Yeh ET. Regulation of apoptosis and cell
carcinoma: a potential target for antisense therapy. J Hepatol cycle progression by MCL1. Differential role of proliferating cell
2006;44:151-7. nuclear antigen. J Biol Chem 2000;275:39458-65.
11. Opferman JT, Iwasaki H, Ong CC, Suh H, Mizuno S, Akashi K, 30. Jamil S, Sobouti R, Hojabrpour P, Raj M, Kast J, Duronio V.
Korsmeyer SJ. Obligate role of anti-apoptotic MCL-1 in the survival A proteolytic fragment of Mcl-1 exhibits nuclear localization
of hematopoietic stem cells. Science 2005;307:1101-4. and regulates cell growth by interaction with Cdk1. Biochem J
12. Kozopas KM, Yang T, Buchan HL, Zhou P, Craig RW. MCL1, a gene 2005;387:659-67.
expressed in programmed myeloid cell differentiation, has sequence 31. De Biasio A, Campos-Olivas R, Sanchez R, Lopez-Alonso JP,
similarity to BCL2. Proc Natl Acad Sci U S A 1993;90:3516-20. Pantoja-Uceda D, Merino N, Villate M, Martin-Garcia JM, Castillo
13. Bae J, Leo CP, Hsu SY, Hsueh AJ. MCL-1S, a splicing variant F, Luque I, Blanco FJ. Proliferating cell nuclear antigen (PCNA)
of the antiapoptotic BCL-2 family member MCL-1, encodes a interactions in solution studied by NMR. PLoS One 2012;7:e48390.
proapoptotic protein possessing only the BH3 domain. J Biol Chem 32. Aichberger KJ, Mayerhofer M, Krauth MT, Skvara H, Florian S,
2000;275:25255-61. Sonneck K, Akgul C, Derdak S, Pickl WF, Wacheck V, Selzer E,
14. Yang T, Kozopas KM, Craig RW. The intracellular distribution and Monia BP, Moriggl R, Valent P, Sillaber C. Identification of mcl-1 as
pattern of expression of Mcl-1 overlap with, but are not identical to, a BCR/ABL-dependent target in chronic myeloid leukemia (CML):
those of Bcl-2. J Cell Biol 1995;128:1173-84. evidence for cooperative antileukemic effects of imatinib and mcl-1
15. Bingle CD, Craig RW, Swales BM, Singleton V, Zhou P, Whyte MK. antisense oligonucleotides. Blood 2005;105:3303-11.
Exon skipping in Mcl-1 results in a bcl-2 homology domain 3 only 33. Breitenbuecher F, Markova B, Kasper S, Carius B, Stauder T, Bohmer
gene product that promotes cell death. J Biol Chem 2000;275:22136- FD, Masson K, Ronnstrand L, Huber C, Kindler T, Fischer T. A novel
46. molecular mechanism of primary resistance to FLT3-kinase inhibitors
16. Rechsteiner M, Rogers SW. PEST sequences and regulation by in AML. Blood 2009;113:4063-73.
proteolysis. Trends Biochem Sci 1996;21:267-71. 34. Zhang T, Zhao C, Luo L, Zhao H, Cheng J, Xu F. The expression
17. Day CL, Chen L, Richardson SJ, Harrison PJ, Huang DC, Hinds of Mcl-1 in human cervical cancer and its clinical significance. Med
MG. Solution structure of prosurvival Mcl-1 and characterization Oncol 2012;29:1985-91.
Hepatoma Research ¦ Volume 3 ¦ July 06, 2017 137