Page 55 - Read Online
P. 55
invasion and metastasis: molecular, biological and clinical perspectives. Cell Sci 2005;118:697-710.
Semin Cancer Biol 2015; pii: S1044-579X(15)00023-1. doi: 10.1016/j. 15. Tu Y, Wu S, Shi X, Chen K, Wu C. Migfilin and Mig-2 link focal
semcancer.2015.03.008. adhesions to filamin and the actin cytoskeleton and function in cell shape
8. Canel M, Serrels A, Frame MC, Brunton VG. E-cadherin-integrin modulation. Cell 2003;113:37-47.
crosstalk in cancer invasion and metastasis. J Cell Sci 2013;126:393-401. 16. Castellano F, Le Clainche C, Patin D, Carlier MF, Chavrier P. A WASp-
9. Chen L, Yang S, Jakoncic J, Zhang JJ, Huang XY. Migrastatin analogues VASP complex regulates actin polymerization at the plasma membrane.
target fascin to block tumour metastasis. Nature 2010;464:1062-6. EMBO J 2001;20:5603-14.
10. Huang X, Ji J, Xue H, Zhang F, Han X, Cai Y, Zhang J, Ji G. Fascin and 17. Sechi AS, Wehland J. ENA/VASP proteins: multifunctional regulators of
cortactin expression is correlated with a poor prognosis in hepatocellular actin cytoskeleton dynamics. Front Biosci 2004;9:1294-310.
carcinoma. Eur J Gastroenterol Hepatol 2012;24:633-9. 18. Kwiatkowski AV, Gertler FB, Loureiro JJ. Function and regulation of
11. Iguchi T, Aishima S, Umeda K, Sanefuji K, Fujita N, Sugimachi K, Ena/VASP proteins. Trends Cell Biol 2003;13:386-92.
Gion T, Taketomi A, Maehara Y, Tsuneyoshi M. Fascin expression in 19. Adams JC. Fascin protrusions in cell interactions. Trends Cardiovasc
progression and prognosis of hepatocellular carcinoma. J Surg Oncol Med 2004;14:221-6.
2009;100:575-9. 20. Tan VY, Lewis SJ, Adams JC, Martin RM. Association of Fascin-1 with
12. Gkretsi V, Bogdanos DP. Experimental evidence of Migfilin as a new mortality, disease progression and metastasis in carcinomas: a systematic
therapeutic target of hepatocellular carcinoma metastasis. Exp Cell Res review and meta-analysis. BMC Med 2013;11:52.
2015;334:219-27. 21. Kulasingam V, Diamandis EP. Fascin-1 is a novel biomarker of
13. Zhang Y, Tu Y, Gkretsi V, Wu C. Migfilin interacts with vasodilator- aggressiveness in some carcinomas. BMC Med 2013;11:53.
stimulated phosphoprotein (VASP) and regulates VASP localization to 22. Hayashi Y, Osanai M, Lee GH. Fascin-1 expression correlates with
cell-matrix adhesions and migration. J Biol Chem 2006;281:12397-407. repression of E-cadherin expression in hepatocellular carcinoma
14. Gkretsi V, Zhang Y, Tu Y, Chen K, Stolz DB, Yang Y, Watkins SC, Wu C. cells and augments their invasiveness in combination with matrix
Physical and functional association of migfilin with cell-cell adhesions. J metalloproteinases. Cancer Sci 2011;102:1228-35.
46 Hepatoma Research | Volume 2 | Issue 2 | February 29, 2016