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Diet history depicted no gastrointestinal (GI) symptoms,   Eastern  Cooperative  Oncology  Group  (ECOG)
            dental or oral problem, or food allergies. The simplified   performance  status  score of  3 indicated  that  the
            nutritional appetite questionnaire (SNAQ) score was   patient was capable of only limited self-care and
            16 hence there was no significant risk of at least   unable to carry out any work activities that was ≥ 50%
                                                                               [13]
            5% weight loss within 6 months.  The patient was   of working hours.  Quality of life (QOL) assessment
                                          [11]
                                                               by short form-36 before LT depicted low level in its
                                     [12]
            alcoholic (CAGE score > 2).  He was recommended    eight dimensions [Figure 1]. [14]
            an  oral  normal  diet  with  supplements  providing
            2700 kcal, 115 g of proteins with salt (2 g) and fluid   Acute post-transplant phase
            restriction (1.5 L/day).  Patients’ intake was 1100 kcal   The altered blood parameters are important for
                               [4]
            and 40 g protein, indicating consumption of 57.6% of   implementing the nutrition therapy plan. Deranged
            the recommended calories.                          biochemical  parameters  in this  phase  are presented
                                                               in Figure 2a-h. The patient had been in intensive care
            Table 1: Biochemical parameters of the patient before the   unit for 3 days. At post-operation day (POD), 1 patient
            transplant                                         was extubated within 24 h and was provided propofol
             Biochemical   Value  Range  Biochemical   Value  Range
             parameter               parameter                 45 mL (1 kcal/mL) and dextrose normal saline 440 mL
             Hb (mg/dL)  8.5   13-17  Na (mmol/L)  134  137-145  (17 kcal/100 mL), KCl 45 mL intravenously. On POD 2
                 3
             WBC (10 /UL)  8.31  4.00-10.00  K (mmol/L)  3.7  3.5-5.1  propofol, 120 mL and KCl 120 mL was given. On
             Platelets   100  150-410  Ca (mg/dL)  8.9  8.4-10.2
              3
             (10 /UL)                                          POD 3 KCl 40 mL along with oral liquids (250 kcal)
             Alb (g/L)   3    3.5-5.0  Mg (mg/dL)  1.5  1.6-2.3  was  given.  On POD 4, he was transferred to the LT
             Bili (D)   0.1   0.2-1.3  P (mg/dL)  4.3  2.5-4.5
             (mg/dL)                                           unit and was given oral high protein normal diet
             Bili (T)   1.5   0.2-1.3  Cl (mmol/L)  106  98-107  with  supplements providing 2,700 kcal and 115 g
             (mg/dL)                                           protein. The patient was not able to complete meals
             Total protein   6.4  6.3-8.2  PT   15.6  8.8-12.3
             (g/L)                                             (especially lunch and dinner), because of nausea and
             ALT/SGPT   23    21-72  INR        1.51           lack  of  appetite.  An  increasing trend of energy and
             (U/L)                                             protein consumption after LT during the hospital stay
             AST/SGOT   34     17-51  CR protein   11.6  0.0-10.0
             (U/L)                   (mg/dL)                   is  indicated  in  Figure  3.  The  patient  met  76.4%  and
             γ glutamyl   28  15-73                            103% of the recommended calorie and protein intake,
             transferase
             (U/L)                                             respectively. The patient was discharged on POD 15,
             Alkaline   63    30-120                           on 2,700 kcal and 115 g of proteins (high protein, low
             phosphates
             (U/L)                                             potassium normal diet) out of which 375 kcal and 36 g of
             Urea (mg/dL)  61  10-50                           protein were from low potassium nutrition supplements
             Cr (mg/dL)  1.6  0.80-1.50                        and about 352 kcal, and 24 g protein was from high
            Hb: hemoglobin; WBC: white blood cell; Alb: albumin; Bili: bilirubin; ALT:   calorie-protein  biscuits.   He  was  recommended  to
                                                                                   [4]
            alanine aminotransferase; AST: aspartate aminotransferase; Cr: creatinine;
            PT: prothrombin time; INR: international normalized ratio; CR protein:   take multivitamins and potassium binding medications,
            C-reactive protein; SGPT: serum glutamic pyruvic transaminase; SGOT:   to monitor glucose regularly, and to avoid the outer
            serum glutamic oxaloacetic transaminase
            Table 2: Nutrition assessment of the patient
             Parameter              Observation  Evaluation
             Anthropometric evaluation
               Weight (kg)             73.9
               Height (cm)             176
               Ideal body weight (kg)  76
                   [7]
               Triceps  (cm)           0.56    Severe
                                               malnutrition
                   [7]
               MAMC  (cm)              22      Mild malnutrition
             SGA [8]
               SGA [8]                  6      Moderate
                                               malnutrition
             Body composition analysis by
             bioelectrical impedance analysis [9]
               Weight (kg)            72.55    Normal
               Fat (%)                 22.5    Normal
               Fat mass                16.3    Normal
               FFM (kg)               56.25    Normal
               Muscle mass (kg)       53.35    Normal          Figure 1: Comparison of quality of life by short form-36 questionnaire pre- and
               BMI                     23.2    Normal          post-transplant. PF: physical functioning; RP: role limitation due to physical
            MAMC: mid-arm muscle circumference; SGA: subjective global assessment;   health; RE: role limitation due to emotional problem; VT: vitality; MH: mental
            FFM: fat-free mass; BMI: body mass index           health; SF: social function; BP: body pain; GH: general health


                  Hepatoma Research | Volume 2 | April 1, 2016                                             99
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