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Page 6 of 10 Xu et al. Chem Synth 2023;3:17 https://dx.doi.org/10.20517/cs.2022.35
Scheme 3. Reaction scope. Reaction conditions: Unless otherwise noted, all reactions were conducted with 5 mol% of L4, 10 mol % of
1
ZnEt , 0.20 mmol 1 and 0.20 mmol 2 in 2 mL MeCN. Isolated yields. The diastereomeric ratio parameter of 3 was detected by H NMR of
2
the crude reaction mixture. The enantiomeric excess (ee) value was determined by HPLC analysis.
