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Topic: Resistance to Cancer Immunotherapy: Mechanisms,
              Advances, Challenges and Opportunities





                                                Dr. Michael Lahn, currently serving as the Chief Medical Officer at iOnctura
                                                SA in Geneva, Switzerland, is a distinguished medical professional with a
                                                robust background in oncology. Graduating with a Medical Doctorate from
                                                the University of Mainz in 1990, Dr. Lahn then served as an Assistenzarzt
                                                at Albert-Ludwigs-Universität Freiburg im Breisgau. In 2019, Dr. Lahn
                                                brought over two decades of industry expertise, garnered from Eli Lilly and
                                                Company, AstraZeneca, and Incyte Corporation, to iOnctura. His impactful
                                                career involves shaping the development of diverse molecular entities,
                                                from small molecule inhibitors like the ALK5 inhibitor galunisertib to the
                      Dr. Michael Lahn          successful registration of osimertinib in non-small cell lung cancer (NSCLC).
                                                Passionate about pioneering cancer therapies, Dr. Lahn is equally dedicated
                iOnctura SA, Geneva, Switzerland.  to mentoring colleagues in the intricate domain of clinical drug development.





                                                Dr. Jordi Rodón is a distinguished expert in early drug development,
                                                biomarker discovery, personalized cancer medicine, and neuro-oncology.
                                                He earned his medical and doctoral degrees from the Universitat Autonoma
                                                de Barcelona. Currently holding the position of Associate Professor in the
                                                Department of Investigational Cancer Therapeutics at The University of
                                                Texas MD Anderson Cancer Center in Houston, TX, Dr. Rodón serves as the
                                                Associate Medical Director in the Department of Institute for Personalized
                                                Cancer Therapy. Additionally, he holds a dual/joint/adjunct appointment as
                                                an Associate Professor in the Department of Genomic Medicine. Dr. Rodón's
                                                commitment to advancing cancer therapeutics is underscored by his role as
                      Dr. Jordi Rodón           the Clinical Co-Director of the Precision Oncology Decision Support Team
               Department of Investigational Cancer   at MD Anderson. He has also contributed significantly to the academic
               Therapeutics, The University of   community as the Co-chair of the Clinical Trials Task Force for Cancer Core
               Texas MD Anderson Cancer Center,   Europe.
               Houston, TX, USA.



                                                Professor Tobias Arkenau stands as a distinguished Consultant Medical
                                                Oncologist, renowned for his expertise in Gastrointestinal Cancers, Drug
                                                Development, and Immunotherapy. Graduating with a medical degree from
                                                Hanover Medical School in Germany in 2000, Prof. Arkenau completed his
                                                oncology training at esteemed institutions, including the Royal Marsden
                                                Hospital. Recognized for his substantial research contributions, he earned
                                                a Fellowship from the Royal College of Physicians. He previously held a
                                                professorship at the University of London, and as the founding Medical
                                                Director and Executive Medical Director of the Sarah Cannon Research
                                                Institute UK. Currently holding the position of Chief Medical Officer and
                Prof. Hendrik Tobias Arkenau    Global Head of Drug Development at Ellipses Pharma, Prof. Arkenau
               Drug Development Unit, Sarah     continues to contribute significantly to the evolution of cancer care and drug
               Cannon Research Institute, London,   development. His medical practice encompasses a wide range of cancers,
               UK.
                                                with a focus on gastrointestinal and skin cancers.
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